BRAF activating mutations involving the β3-αC loop in V600E-negative anaplastic pleomorphic xanthoastrocytoma
Sign Up to like & getrecommendations! Published in 2018 at "Acta Neuropathologica Communications"
DOI: 10.1186/s40478-018-0525-1
Abstract: Anaplastic pleomorphic xanthoastrocytoma (A-PXA, WHO grade III) is a newly defined entity with highgrade histopathologic features and a propensity for recurrence [6]. While PXA with low-grade histology (WHO grade II) can harbor a recurrent valine-toglutamic… read more here.
Keywords: v600e negative; braf; kinase domain; anaplastic pleomorphic ... See more keywords
Identification of BRAF p. V600E-Mutant and Wild-Type by MR Imaging in Pleomorphic Xanthoastrocytoma and Anaplastic Pleomorphic Xanthoastrocytoma
Sign Up to like & getrecommendations! Published in 2021 at "American Journal of Neuroradiology"
DOI: 10.3174/ajnr.a7324
Abstract: BACKGROUND AND PURPOSE: Compared with BRAF p. V600E wild-type pleomorphic xanthoastrocytoma, BRAF p. V600E-mutant pleomorphic xanthoastrocytoma showed a higher survival rate. In this study, we focused on finding preoperative MR imaging differences between BRAF p.… read more here.
Keywords: v600e mutant; pleomorphic xanthoastrocytoma; xanthoastrocytoma; anaplastic pleomorphic ... See more keywords