Anastrozole-Induced Dermatitis: Report of a Woman with an Anastrozole-Associated Dermatosis and a Review of Aromatase Inhibitor-Related Cutaneous Adverse Events
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DOI: 10.1007/s13555-020-00353-3
Abstract: Anastrozole is an aromatase inhibitor. Anastrozole competitively inhibits the aromatase enzyme, which synthesizes estrogen. It is used for estrogen receptor-positive breast cancers. A woman with breast cancer and anastrozole-induced dermatitis is described; the cutaneous side… read more here.
Keywords: aromatase inhibitor; induced dermatitis; anastrozole induced; aromatase ... See more keywords
Kinin B2 and B1 Receptors Activation Sensitize the TRPA1 Channel Contributing to Anastrozole-Induced Pain Symptoms
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DOI: 10.3390/pharmaceutics15041136
Abstract: Aromatase inhibitors (AIs) cause symptoms of musculoskeletal pain, and some mechanisms have been proposed to explain them. However, signaling pathways downstream from kinin B2 (B2R) and B1 (B1R) receptor activation and their possible sensitizing of… read more here.
Keywords: b1r; trpa1 channel; pain; anastrozole induced ... See more keywords