Improving Wastewater-Based Tobacco Use Estimates Using Anabasine.
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DOI: 10.1021/acs.est.3c01510
Abstract: In wastewater-based epidemiology (WBE), nicotine metabolites have been used as biomarkers for monitoring tobacco use. Recently, the minor tobacco alkaloids anabasine and anatabine have been suggested as more specific biomarkers for tobacco use since nicotine… read more here.
Keywords: wastewater based; anatabine; tobacco; use ... See more keywords
Systems biology reveals anatabine to be an NRF2 activator
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DOI: 10.3389/fphar.2022.1011184
Abstract: Anatabine, an alkaloid present in plants of the So lanaceae family (including tobacco and eggplant), has been shown to ameliorate chronic inflammatory conditions in mouse models, such as Alzheimer’s disease, Hashimoto’s thyroiditis, multiple sclerosis, and… read more here.
Keywords: biology reveals; anatabine; pharmacology; systems biology ... See more keywords
Differentiating the Neuropharmacological Properties of Nicotinic Acetylcholine Receptor-Activating Alkaloids
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DOI: 10.3389/fphar.2022.668065
Abstract: Alkaloids that target nicotinic acetylcholine receptors (nAChR) are of great interest because of the critical role they play in mood and anxiety. However, understanding of the neuropharmacological effects of nicotinic alkaloids, such as cotinine and… read more here.
Keywords: anatabine; cotinine anatabine; anxiolytic like; differentiating neuropharmacological ... See more keywords
Anabasine and Anatabine Exposure Attributable to Cigarette Smoking: National Health and Nutrition Examination Survey (NHANES) 2013–2014
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DOI: 10.3390/ijerph19159744
Abstract: Anabasine and anatabine are minor alkaloids in tobacco products and are precursors for tobacco-specific nitrosamines (TSNAs). The levels of these two compounds have been used to differentiate tobacco product sources, monitor compliance with smoking cessation… read more here.
Keywords: anatabine; urinary anabasine; anabasine anatabine; tobacco ... See more keywords