APOL1 Risk Variants, Acute Kidney Injury, and Death in Participants With African Ancestry Hospitalized With COVID-19 From the Million Veteran Program.
Sign Up to like & getrecommendations! Published in 2022 at "JAMA internal medicine"
DOI: 10.1001/jamainternmed.2021.8538
Abstract: Importance Coronavirus disease 2019 (COVID-19) confers significant risk of acute kidney injury (AKI). Patients with COVID-19 with AKI have high mortality rates. Objective Individuals with African ancestry with 2 copies of apolipoprotein L1 (APOL1) variants… read more here.
Keywords: risk; ancestry; risk group; risk variants ... See more keywords
Clinical Characterization of Copy Number Variants Associated With Neurodevelopmental Disorders in a Large-scale Multiancestry Biobank.
Sign Up to like & getrecommendations! Published in 2022 at "JAMA psychiatry"
DOI: 10.1001/jamapsychiatry.2021.4080
Abstract: Importance Past studies identified rare copy number variants (CNVs) as risk factors for neurodevelopmental disorders (NDDs), including autism spectrum disorder and schizophrenia. However, the clinical characterization of NDD CNVs is understudied in population cohorts unselected… read more here.
Keywords: cnvs; ancestry; multiancestry biobank; ndd cnvs ... See more keywords
Identification of Novel, Replicable Genetic Risk Loci for Suicidal Thoughts and Behaviors Among US Military Veterans.
Sign Up to like & getrecommendations! Published in 2022 at "JAMA psychiatry"
DOI: 10.1001/jamapsychiatry.2022.3896
Abstract: Importance Suicide is a leading cause of death; however, the molecular genetic basis of suicidal thoughts and behaviors (SITB) remains unknown. Objective To identify novel, replicable genomic risk loci for SITB. Design, Setting, and Participants… read more here.
Keywords: risk loci; ancestry; cross ancestry; military veterans ... See more keywords
Comparing self-reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models.
Sign Up to like & getrecommendations! Published in 2025 at "Molecular oncology"
DOI: 10.1002/1878-0261.70013
Abstract: While the incidence of endometrial cancer is increasing among all US women, Black women face higher mortality rates. The reasons for this remain unclear. In this study, whole genome differential methylation analysis, along with state‐of‐the‐art… read more here.
Keywords: african ancestry; genetic ancestry; learning models; machine learning ... See more keywords
Morphoscopic ancestry estimates in Filipino crania using multivariate probit regression models.
Sign Up to like & getrecommendations! Published in 2020 at "American journal of physical anthropology"
DOI: 10.1002/ajpa.24008
Abstract: OBJECTIVES Probit has not been applied to ancestry estimation in forensic anthropology. The goals of this study were to: (1) evaluate the performance of probit analysis as a classification tool for ancestry estimation using ordinal… read more here.
Keywords: anthropology; probit; filipino crania; multivariate probit ... See more keywords
Contrasting the ancestry patterns of three distinct population groups from the northernmost region of South America.
Sign Up to like & getrecommendations! Published in 2020 at "American journal of physical anthropology"
DOI: 10.1002/ajpa.24130
Abstract: Colombia, located in the north of the South American subcontinent is a country of great interest for population genetic studies given its high ethnic and cultural diversity represented by the admixed population, 102 indigenous peoples… read more here.
Keywords: contrasting ancestry; ancestry; population; native american ... See more keywords
The need to incorporate human variation and evolutionary theory in forensic anthropology: A call for reform.
Sign Up to like & getrecommendations! Published in 2021 at "American journal of physical anthropology"
DOI: 10.1002/ajpa.24384
Abstract: In 1992, Norm Sauer called for a language shift in which practitioners would move away from the socially loaded term "race" and replace it with the less provocative term "ancestry." While many heeded the call… read more here.
Keywords: anthropology; human variation; ancestry; population ... See more keywords
Admixture in Africanized honey bees (Apis mellifera) from Panamá to San Diego, California (U.S.A.)
Sign Up to like & getrecommendations! Published in 2022 at "Ecology and Evolution"
DOI: 10.1002/ece3.8580
Abstract: Abstract The Africanized honey bee (AHB) is a New World amalgamation of several subspecies of the western honey bee (Apis mellifera), a diverse taxon historically grouped into four major biogeographic lineages: A (African), M (Western… read more here.
Keywords: honey; ancestry; admixture; honey bee ... See more keywords
Development of a SNP panel for predicting biogeographical ancestry and phenotype using massively parallel sequencing
Sign Up to like & getrecommendations! Published in 2018 at "ELECTROPHORESIS"
DOI: 10.1002/elps.201800243
Abstract: Inferring ancestry and physical characteristics of an unknown individual can contribute to the direction of the investigation and to clarify the event for unknown contributors, cold cases or identification of missing persons and disaster victims.… read more here.
Keywords: phenotype; massively parallel; snp panel; panel ... See more keywords
Joint genotype‐ and ancestry‐based genome‐wide association studies in admixed populations
Sign Up to like & getrecommendations! Published in 2017 at "Genetic Epidemiology"
DOI: 10.1002/gepi.22056
Abstract: In genome‐wide association studies (GWAS) genetic loci that influence complex traits are localized by inspecting associations between genotypes of genetic markers and the values of the trait of interest. On the other hand, admixture mapping,… read more here.
Keywords: genome wide; association studies; genotype ancestry; ancestry ... See more keywords
North American genetic counselors' approach to collecting and using ancestry in clinical practice
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Genetic Counseling"
DOI: 10.1002/jgc4.1655
Abstract: Current guidelines from the National Society of Genetic Counselors (NSGC) recommend that patients' ancestry be obtained when taking a family history. However, no study has explored how consistently genetic counselors obtain or utilize this information.… read more here.
Keywords: information; practice; ancestry; genetic counselors ... See more keywords