An ancestry‐based approach for detecting interactions
Sign Up to like & getrecommendations! Published in 2018 at "Genetic Epidemiology"
DOI: 10.1002/gepi.22087
Abstract: Epistasis and gene‐environment interactions are known to contribute significantly to variation of complex phenotypes in model organisms. However, their identification in human association studies remains challenging for myriad reasons. In the case of epistatic interactions,… read more here.
Keywords: detecting interactions; approach detecting; ancestry based; epidemiology ... See more keywords
Ancestry-based differences in hereditary cancer genetic testing.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2017.35.15_suppl.e13107
Abstract: e13107Background: Ancestry-based disparities in genetic testing for the hereditary breast and ovarian cancer (HBOC) genes BRCA1/2 have been well documented, but it is unclear whether this extends to other cancer-risk genes. Given reduced costs and… read more here.
Keywords: differences hereditary; genetic testing; ancestry based; cancer ... See more keywords
Assortative Mating on Ancestry-Variant Traits in Admixed Latin American Populations
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DOI: 10.3389/fgene.2019.00359
Abstract: Assortative mating is a universal feature of human societies, and individuals from ethnically diverse populations are known to mate assortatively based on similarities in genetic ancestry. However, little is currently known regarding the exact phenotypic… read more here.
Keywords: latin american; assortative mating; mating; ancestry based ... See more keywords