Assessment of the potential role of natural selection in type 2 diabetes and related traits across human continental ancestry groups: comparison of phenotypic with genotypic divergence
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DOI: 10.1007/s00125-020-05272-8
Abstract: Prevalence of type 2 diabetes differs among human ancestry groups, and many hypotheses invoke differential natural selection to account for these differences. We sought to assess the potential role of differential natural selection across major… read more here.
Keywords: type diabetes; ancestry groups; selection; natural selection ... See more keywords
Ancestry-dependent patterns of somatic mosaicism and clonal hematopoiesis mutations in over 125,000 individuals reveal distinct cancer associations
Sign Up to like & getrecommendations! Published in 2025 at "Human Genomics"
DOI: 10.1186/s40246-025-00847-1
Abstract: Somatic mosaicism (SM), the presence of somatic mutations, is classified as clonal hematopoiesis (CH) when it occurs in hematopoietic cells at an age-related rate. CH is associated with risk for hematologic malignancies and cardiovascular disease,… read more here.
Keywords: ancestry groups; somatic mosaicism; clonal hematopoiesis; chip ... See more keywords