Selective targeting of metastatic ovarian cancer using an engineered anthrax prodrug activated by membrane-anchored serine proteases
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DOI: 10.1073/pnas.2201423119
Abstract: Significance Ovarian cancer is the most lethal gynecological cancer. Clinically approved chemotherapies aim to slow or stop tumor growth; however, cancer cells continue to evolve between chemotherapy cycles, acquiring properties that allow cell survival and… read more here.
Keywords: metastatic ovarian; ovarian cancer; anchored serine; membrane anchored ... See more keywords