Anchoring Chromatin Loops to Cancer.
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DOI: 10.1016/j.devcel.2017.07.013
Abstract: Although some genomic rearrangements are caused by replication or transcription, the etiology of others is unclear. Reporting in Cell, Canela et al. (2017) reveal that type II topoisomerase-mediated release of torsional strain at chromosomal loop anchors… read more here.
Keywords: loops cancer; chromatin loops; anchoring chromatin; etiology ... See more keywords