Myristoylation, an Ancient Protein Modification Mirroring Eukaryogenesis and Evolution.
Sign Up to like & getrecommendations! Published in 2020 at "Trends in biochemical sciences"
DOI: 10.1016/j.tibs.2020.03.007
Abstract: N-myristoylation (MYR) is a crucial fatty acylation catalyzed by N-myristoyltransferases (NMTs) that is likely to have appeared over 2 billion years ago. Proteome-wide approaches have now delivered an exhaustive list of substrates undergoing MYR across… read more here.
Keywords: myristoylation ancient; ancient protein; evolution; eukaryogenesis ... See more keywords
Contributions of substitutions and indels to the structural variations in ancient protein superfamilies
Sign Up to like & getrecommendations! Published in 2018 at "BMC Genomics"
DOI: 10.1186/s12864-018-5178-8
Abstract: BackgroundQuantitative evaluation of protein structural evolution is important for our understanding of protein biological functions and their evolutionary adaptation, and is useful in guiding protein engineering. However, compared to the models for sequence evolution, the… read more here.
Keywords: protein; structural variations; ancient protein; substitutions indels ... See more keywords