Synthesis and cytotoxicity of novel 14α-O-(andrographolide-3-subsitutedisoxazole-5-carboxylate) derivatives.
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DOI: 10.1080/14786419.2020.1736060
Abstract: Simple and efficient method was established for the synthesis of a new family of 14α-O-(andrographolide-3-subsitutedisoxazole-5-carboxylate) derivatives (10a-j) from naturally occurring andrographolide (1) by selective esterification with propiolic acid at C-14 using protection and deprotection strategy… read more here.
Keywords: synthesis cytotoxicity; subsitutedisoxazole carboxylate; andrographolide subsitutedisoxazole; cytotoxicity ... See more keywords