Entrapping bupivacaine-loaded emulsions in a crosslinked-hydrogel increases anesthetic effect and duration in a rat sciatic nerve block model.
Sign Up to like & getrecommendations! Published in 2020 at "International journal of pharmaceutics"
DOI: 10.1016/j.ijpharm.2020.119703
Abstract: The purpose of this research was to evaluate a novel long-acting bupivacaine delivery system for control of postoperative pain. Bupivacaine-loaded lipid emulsion (BLE) droplets were created by high-speed homogenization. The BLE droplets were then entrapped… read more here.
Keywords: rat sciatic; ble droplets; bupivacaine loaded; bupivacaine ... See more keywords
Assessment of the anesthetic effect of modified pentothal sodium solution on Sprague-Dawley rats
Sign Up to like & getrecommendations! Published in 2022 at "Open Life Sciences"
DOI: 10.1515/biol-2022-0050
Abstract: Abstract Clinically, pentothal sodium has been widely used for primary and general anesthesia induction. Also, it has been used to effectively inhibit convulsion. Pentothal sodium has a strong inhibitory effect on the respiratory center, excessive… read more here.
Keywords: anesthetic effect; time; sodium; pentothal sodium ... See more keywords