General Anesthetics Regulate Autophagy via Modulating the Inositol 1,4,5-Trisphosphate Receptor: Implications for Dual Effects of Cytoprotection and Cytotoxicity
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DOI: 10.1038/s41598-017-11607-0
Abstract: General anesthetics are both neuroprotective and neurotoxic with unclear mechanisms. General anesthetics may control cell survival via their effects on autophagy by activation of type 1 inositol triphosphate receptor (InsP3R-1). DT40 or SH-SY5Y cells with… read more here.
Keywords: regulate autophagy; propofol; cytoprotection; anesthetics regulate ... See more keywords