Reactive Oxygen Species‐Triggered Hydrogen Sulfide Release and Cancer‐Selective Antiproliferative Effect of Anethole Dithiolethione‐Containing Polymeric Micelles
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DOI: 10.1002/adhm.202201836
Abstract: Hydrogen sulfide (H2S) is a gaseous signaling molecule in the human body and has attracted attention in cancer therapy due to its regulatory roles in cancer cell proliferation and migration. Accumulating evidence suggests that continuous… read more here.
Keywords: anethole dithiolethione; polymeric micelles; release; hydrogen sulfide ... See more keywords
Slow-Release H2S Donor Anethole Dithiolethione Protects Liver From Lipotoxicity by Improving Fatty Acid Metabolism
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DOI: 10.3389/fphar.2020.549377
Abstract: “Lipotoxicity” induced by free fatty acids (FAs) plays a central role in the pathogenesis of many metabolic diseases, with few treatment options available today. Hydrogen sulfide (H2S), a novel gaseous signaling molecule, has been reported… read more here.
Keywords: lipotoxicity; metabolism; release h2s; fatty acid ... See more keywords