Aortic aneurysm and dissection in pregnancy: A case report
Sign Up to like & getrecommendations! Published in 2020 at "Case Reports in Women's Health"
DOI: 10.1016/j.crwh.2020.e00261
Abstract: We describe a 24-year-old pregnant woman at 34 weeks of gestation who presented to a community hospital with sharp chest pain radiating to her back. She was found to have a 6 cm ascending aortic… read more here.
Keywords: pregnancy; aneurysm dissection; aortic aneurysm; case ... See more keywords
Programmed cell death in aortic aneurysm and dissection: A potential therapeutic target.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of molecular and cellular cardiology"
DOI: 10.1016/j.yjmcc.2021.09.010
Abstract: Rupture of aortic aneurysm and dissection (AAD) remains a leading cause of death. Progressive smooth muscle cell (SMC) loss is a crucial feature of AAD that contributes to aortic dysfunction and degeneration, leading to aortic… read more here.
Keywords: death; aneurysm dissection; aortic aneurysm; programmed cell ... See more keywords
Targeting endothelial tight junctions to predict and protect thoracic aortic aneurysm and dissection.
Sign Up to like & getrecommendations! Published in 2023 at "European heart journal"
DOI: 10.1093/eurheartj/ehac823
Abstract: AIMS Whether changes in endothelial tight junctions (TJs) lead to the formation of thoracic aortic aneurysm and dissection (TAAD) and serve as an early indicator and therapeutic target remains elusive. METHODS AND RESULTS Single-cell RNA… read more here.
Keywords: aneurysm dissection; tight junctions; thoracic aortic; thoracic aortas ... See more keywords
Early Morphofunctional Changes in AngII-Infused Mice Contribute to Regional Onset of Aortic Aneurysm and Dissection
Sign Up to like & getrecommendations! Published in 2020 at "Journal of vascular research"
DOI: 10.1159/000509545
Abstract: Aortic aneurysms and dissections are silent and lethal conditions, whose pathogenesis remains incompletely understood. Although angiotensin II (AngII)-infused ApoE−/− mice have been widely used to study aortic aneurysm and dissection, early morphofunctional alterations preceding the… read more here.
Keywords: morphofunctional changes; aneurysm dissection; aortic aneurysm; dissection ... See more keywords
Further Evidence Supporting a Protective Role of Transforming Growth Factor-β (TGFβ) in Aortic Aneurysm and Dissection.
Sign Up to like & getrecommendations! Published in 2017 at "Arteriosclerosis, thrombosis, and vascular biology"
DOI: 10.1161/atvbaha.117.310031
Abstract: Aortic disease arises from abnormalities in size or structure of the vessel wall. An (fusiform) aneurysm is a localized dilatation of the aorta, usually defined as >150% of the normal diameter for a given segment.… read more here.
Keywords: transforming growth; aneurysm dissection; disease; growth factor ... See more keywords
Early outcomes of patients transferred with ruptured suprarenal aneurysm or dissection
Sign Up to like & getrecommendations! Published in 2018 at "Annals of the Royal College of Surgeons of England"
DOI: 10.1308/rcsann.2018.0014
Abstract: OBJECTIVE Despite centralisation of the provision of vascular care, not all areas in England and Wales are able to offer emergency treatment for patients with acute conditions affecting the aorta proximal to the renal arteries.… read more here.
Keywords: outcomes patients; aneurysm dissection; early outcomes; ruptured suprarenal ... See more keywords
Assessing serum levels of SM22α as a new biomarker for patients with aortic aneurysm/dissection
Sign Up to like & getrecommendations! Published in 2022 at "PLoS ONE"
DOI: 10.1371/journal.pone.0264942
Abstract: Background Aortic aneurysm/dissection (AAD) is now encountered more often because of the increasing prevalence of atherosclerosis and hypertension in the population. Despite many therapeutic improvements, in particular timely and successful surgery, in-hospital mortality rates are… read more here.
Keywords: aneurysm dissection; serum; aad; serum sm22 ... See more keywords
Artificial Intelligence Uncovers Natural MMP Inhibitor Crocin as a Potential Treatment of Thoracic Aortic Aneurysm and Dissection
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cardiovascular Medicine"
DOI: 10.3389/fcvm.2022.871486
Abstract: Thoracic aortic aneurysm and dissection (TAAD) is a lethal cardiovascular condition without effective pharmaceutical therapy. Identifying novel drugs that target the key pathogenetic components is an urgent need. Bioinformatics analysis of pathological studies indicated “extracellular… read more here.
Keywords: mmp inhibitor; artificial intelligence; thoracic aortic; aortic aneurysm ... See more keywords
Genome-Wide Identification of Associations of Circulating Molecules With Spontaneous Coronary Artery Dissection and Aortic Aneurysm and Dissection
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cardiovascular Medicine"
DOI: 10.3389/fcvm.2022.874912
Abstract: Circulating proteins play functional roles in various biological processes and disease pathogenesis. The aim of this study was to highlight circulating proteins associated with aortic aneurysm and dissection (AAD) and spontaneous coronary artery dissection (SCAD).… read more here.
Keywords: aneurysm dissection; associations circulating; spontaneous coronary; dissection ... See more keywords
Tracking an Elusive Killer: State of the Art of Molecular-Genetic Knowledge and Laboratory Role in Diagnosis and Risk Stratification of Thoracic Aortic Aneurysm and Dissection
Sign Up to like & getrecommendations! Published in 2022 at "Diagnostics"
DOI: 10.3390/diagnostics12081785
Abstract: The main challenge in diagnosing and managing thoracic aortic aneurysm and dissection (TAA/D) is represented by the early detection of a disease that is both deadly and “elusive”, as it generally grows asymptomatically prior to… read more here.
Keywords: aneurysm dissection; role; diagnosis; thoracic aortic ... See more keywords
Is There Enough Evidence to Support the Role of Glycosaminoglycans and Proteoglycans in Thoracic Aortic Aneurysm and Dissection?—A Systematic Review
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23169200
Abstract: Altered proteoglycan (PG) and glycosaminoglycan (GAG) distribution within the aortic wall has been implicated in thoracic aortic aneurysm and dissection (TAAD). This review was conducted to identify literature reporting the presence, distribution and role of… read more here.
Keywords: aneurysm dissection; role; thoracic aortic; enough evidence ... See more keywords