Genetic basis of hereditary thoracic aortic aneurysms and dissections.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of cardiology"
DOI: 10.1016/j.jjcc.2019.03.014
Abstract: Recent advances in DNA sequencing technology have identified several causative genes for hereditary thoracic aortic aneurysms and dissections (TAADs), including Marfan syndrome (MFS), Loeys-Dietz syndrome, vascular Ehlers-Danlos syndrome, and familial non-syndromic TAADs. Syndromic TAADs are… read more here.
Keywords: hereditary taads; hereditary thoracic; genetics; aneurysms dissections ... See more keywords
Heritable Thoracic Aortic Aneurysms and Dissections.
Sign Up to like & getrecommendations! Published in 2021 at "Techniques in vascular and interventional radiology"
DOI: 10.1016/j.tvir.2021.100747
Abstract: A large portion of thoracic aortic aneurysms and dissections (TAAD) have a genetic etiology. In recent decades, numerous genes have been identified as associated with heritable thoracic aortic aneurysms and dissections (HTAAD), providing important insights… read more here.
Keywords: thoracic aortic; etiology; heritable thoracic; aneurysms dissections ... See more keywords
Genetic diversity and pathogenic variants as possible predictors of severity in a French sample of nonsyndromic heritable thoracic aortic aneurysms and dissections (nshTAAD)
Sign Up to like & getrecommendations! Published in 2019 at "Genetics in Medicine"
DOI: 10.1038/s41436-019-0444-y
Abstract: PurposeHeritable thoracic aortic aneurysms and dissections (hTAAD) are life-threatening complications of well-known syndromic diseases or underdiagnosed nonsyndromic heritable forms (nshTAAD). Both have an autosomal dominant transmission and are genetically heterogeneous. Our objective was to describe… read more here.
Keywords: nonsyndromic heritable; pathogenic; aneurysms dissections; aortic aneurysms ... See more keywords
National trends in thoracic aortic aneurysms and dissections in patients with Marfans and Ehlers Danlos syndrome
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Cardiac Surgery"
DOI: 10.1111/jocs.16853
Abstract: Connective tissue disorders predispose patients to earlier aortic dissections and aneurysms. However, there is limited large cohort data given its low incidence. read more here.
Keywords: aortic aneurysms; dissections patients; thoracic aortic; national trends ... See more keywords
A validated mouse model capable of recapitulating the protective effects of female sex hormones on ascending aortic aneurysms and dissections (AADs)
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DOI: 10.14814/phy2.14631
Abstract: Fewer females develop AADs (ascending aortic aneurysms and dissections) and the reasons for this protection remain poorly understood. The present study seeks to develop a mouse model that may be utilized to address this sexual… read more here.
Keywords: aneurysms dissections; aortic aneurysms; model; bapn angii ... See more keywords
Imaging Techniques for Aortic Aneurysms and Dissections in Mice: Comparisons of Ex Vivo, In Situ, and Ultrasound Approaches
Sign Up to like & getrecommendations! Published in 2022 at "Biomolecules"
DOI: 10.3390/biom12020339
Abstract: Aortic aneurysms and dissections are life-threatening conditions that have a high risk for lethal bleeding and organ malperfusion. Many studies have investigated the molecular basis of these diseases using mouse models. In mice, ex vivo,… read more here.
Keywords: vivo situ; aneurysms dissections; situ ultrasound; imaging techniques ... See more keywords