Circ‐Zfp644 acts as a pro‐hypertrophic mediator in an Ang‐II induced in vitro myocardial hypertrophy model
Sign Up to like & getrecommendations! Published in 2021 at "Cell Biology International"
DOI: 10.1002/cbin.11569
Abstract: Cardiac hypertrophy (CH) is a common risk factor for heart failure and even sudden cardiac death. Molecules have emerged as vital regulators in cardiac disorders. LIM domain kinase 1 (Limk1) is reported as a pro‐fibrotic… read more here.
Keywords: zfp644; mir; model; circ zfp644 ... See more keywords
Melatonin counteracts necroptosis and pulmonary edema in cadmium‐induced chronic lung injury through the inhibition of angiotensin II
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Biochemical and Molecular Toxicology"
DOI: 10.1002/jbt.23163
Abstract: The renin‐angiotensin system (RAS) is an important regulator in pulmonary physiology. In our study, we identified the efficacy of melatonin to control the RAS in cadmium (Cd) induced chronic lung injury in a mouse model.… read more here.
Keywords: cadmium induced; angiotensin; lung; ang ... See more keywords
Uric acid and angiotensin II additively promote inflammation and oxidative stress in human proximal tubule cells by activation of toll‐like receptor 4
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.27929
Abstract: Renal proximal tubular cells (PTECs) participate in several mechanisms of innate immunity, express toll‐like receptors (TLRs), and proinflammatory cytokines. Hyperuricemia may be a promoter of inflammation and renal damage. Angiotensin II (Ang II) modulate immune… read more here.
Keywords: toll like; uric acid; inflammation; tlr4 ... See more keywords
Ellagic acid protects against angiotensin II‐induced hypertrophic responses through ROS‐mediated MAPK pathway in H9c2 cells
Sign Up to like & getrecommendations! Published in 2024 at "Environmental Toxicology"
DOI: 10.1002/tox.24170
Abstract: The early myocardial response of hypertension is an elevation of angiotensin‐II (Ang‐II) concentration, leading to heart failure and cardiac hypertrophy. This hypertrophic event of the heart is mediated by the interaction of Ang type 1… read more here.
Keywords: induced hypertrophic; ellagic acid; hypertrophic responses; h9c2 cells ... See more keywords
A Primer to Angiotensin Peptide Isolation, Stability, and Analysis by Nano-Liquid Chromatography with Mass Detection.
Sign Up to like & getrecommendations! Published in 2017 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-7030-8_14
Abstract: The renin-angiotensin system (RAS) is an important element of cardiovascular and renal physiology and targeting the RAS by renin inhibitors, angiotensin (Ang) converting enzyme (ACE) inhibitors and Ang II type 1 receptor antagonists is effective… read more here.
Keywords: ang ang; ang; mass detection; angiotensin ... See more keywords
Emerging clinical evidence of a dual role for Ang-2 and VEGF-A blockade with faricimab in retinal diseases
Sign Up to like & getrecommendations! Published in 2024 at "Graefe's Archive for Clinical and Experimental Ophthalmology"
DOI: 10.1007/s00417-024-06695-4
Abstract: Anti-vascular endothelial growth factor (VEGF) therapies have transformed the treatment of retinal diseases. However, VEGF signaling is only one component of the complex, multifactorial pathophysiology of retinal diseases, and many patients have residual disease activity… read more here.
Keywords: vascular instability; ang; retinal diseases; ang vegf ... See more keywords
Targeting myocardial inflammation: investigating the therapeutic potential of atrial natriuretic peptide in atrial fibrosis
Sign Up to like & getrecommendations! Published in 2024 at "Molecular Biology Reports"
DOI: 10.1007/s11033-024-09393-w
Abstract: Atrial Fibrillation (AF), a prevalent arrhythmic condition, is intricately associated with atrial fibrosis, a major pathological contributor. Central to the development of atrial fibrosis is myocardial inflammation. This study focuses on Atrial Natriuretic Peptide (ANP)… read more here.
Keywords: atrial natriuretic; fibrosis; myocardial inflammation; ang ... See more keywords
Longitudinal study of angiotensin peptides in normal and pre-eclamptic pregnancy
Sign Up to like & getrecommendations! Published in 2020 at "Endocrine"
DOI: 10.1007/s12020-020-02296-3
Abstract: Purpose To address whether differential regulation of the renin-angiotensin-aldosterone system occurs in pre-eclampsia, we performed an analysis of the time course of circulating and urinary profiles of the vasoconstrictor (Ang II) and the vasodilator [Ang-(1–7)]… read more here.
Keywords: gestation; weeks gestation; peptides normal; pre eclamptic ... See more keywords
125I-Angiotensin 1–7 binds to a different site than angiotensin 1–7 in tissue membrane preparations
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DOI: 10.1007/s12020-020-02572-2
Abstract: To study the receptor for Angiotensin (Ang) 1–7 using a radioligand (125I-Ang 1–7)-binding assay. For more than a decade, Mas has been viewed as the receptor for Ang 1–7; however, Ang 1–7 binding has not… read more here.
Keywords: membrane preparations; tissue membrane; 125i ang; ang ... See more keywords
Angiopoietin-2 as a Prognostic Factor in Patients with Incurable Stage IV Colorectal Cancer
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DOI: 10.1007/s12029-020-00392-1
Abstract: Purpose Angiopoietin (Ang), a ligand of the endothelium-specific receptor Tie-2 system, is associated with tumor growth and progression that depend on angiogenesis. The present study aimed to investigate the predictive potential of angiopoietin factors in… read more here.
Keywords: incurable stage; stage colorectal; colorectal cancer; ang ... See more keywords
Angiotensin II Causes Neuronal Damage in Stretch-Injured Neurons: Protective Effects of Losartan, an Angiotensin T1 Receptor Blocker
Sign Up to like & getrecommendations! Published in 2017 at "Molecular Neurobiology"
DOI: 10.1007/s12035-017-0812-z
Abstract: Angiotensin II (Ang II) is a mediator of oxidative stress via activation/induction of reactive oxygen and nitrogen species-generating enzymes, NADPH oxidase (NOX) and inducible nitric oxide synthase (iNOS). We investigated the hypothesis that overproduction of… read more here.
Keywords: stretch; angiotensin; ang; receptor ... See more keywords