Myocardial Angiotensin Metabolism in End-Stage HeartĀ Failure.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of the American College of Cardiology"
DOI: 10.1016/j.jacc.2021.01.052
Abstract: BACKGROUND The myocardium exhibits an adaptive tissue-specific renin-angiotensin system (RAS), and local dysbalance may circumvent the desired effects of pharmacologic RAS inhibition, a mainstay of heart failure with reduced ejection fraction (HFrEF) therapy. OBJECTIVES This… read more here.
Keywords: angiii; heart; heart failure; angiotensin ... See more keywords
The Novel AT2 Receptor Agonist Ī²-Pro7-AngIII Exerts Cardiac and Renal Anti-Fibrotic and Anti-Inflammatory Effects in High Salt-Fed Mice
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms232214039
Abstract: A high salt (HS) diet is associated with an increased risk for cardiovascular diseases (CVDs) and fibrosis is a key contributor to the organ dysfunction involved in CVDs. The activation of the renin angiotensin type… read more here.
Keywords: pro7 angiii; anti inflammatory; angiii; inflammatory effects ... See more keywords