Vascular leakage caused by loss of Akt1 is associated with impaired mural cell coverage
Sign Up to like & getrecommendations! Published in 2019 at "FEBS Open Bio"
DOI: 10.1002/2211-5463.12621
Abstract: Angiogenesis plays a critical role in embryo development, tissue repair, tumor growth and wound healing. In the present study, we investigated the role of the serine/threonine kinase Akt in angiogenesis. Silencing of Akt1 in human… read more here.
Keywords: angiogenesis; mural cell; akt1; cell coverage ... See more keywords
Bioactive Poly(octanediol-citrate-polyglycol) Accelerates Skin Regeneration through M2 Polarization Immunomodulating and Early Angiogenesis.
Sign Up to like & getrecommendations! Published in 2022 at "Advanced healthcare materials"
DOI: 10.1002/adhm.202101931
Abstract: The inhibition of inflammation and the promotion of early angiogenesis have been paid much attention in skin tissue engineering. Citric acid-based biomaterials are widely used in tissue engineering due to their bioactive structure and biocompatibility,… read more here.
Keywords: citrate; angiogenesis; polarization; skin regeneration ... See more keywords
A ROS‐Responsive Liposomal Composite Hydrogel Integrating Improved Mitochondrial Function and Pro‐Angiogenesis for Efficient Treatment of Myocardial Infarction
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DOI: 10.1002/adhm.202200990
Abstract: Mitochondrial dysfunction of cardiomyocytes (CMs) has been identified as a significant pathogenesis of early myocardial infarction (MI). However, only a few agents or strategies have been developed to improve mitochondrial dysfunction for the effective MI… read more here.
Keywords: hydrogel; liposomal composite; mitochondrial dysfunction; treatment ... See more keywords
Dapagliflozin‐Loaded Exosome Mimetics Facilitate Diabetic Wound Healing by HIF‐1α‐Mediated Enhancement of Angiogenesis
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DOI: 10.1002/adhm.202202751
Abstract: Angiogenesis plays a critical role in diabetic wound healing. However, no effective strategies have been developed to target endothelial cells (ECs) to facilitate diabetic wound healing. Dapagliflozin (DA) as a sodium‐glucose linked transporter 2 (SGLT2)… read more here.
Keywords: wound healing; facilitate diabetic; diabetic wound; angiogenesis ... See more keywords
Silicon‐Enhanced Adipogenesis and Angiogenesis for Vascularized Adipose Tissue Engineering
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DOI: 10.1002/advs.201800776
Abstract: Abstract The enhancement of adipogenic differentiation of bone marrow mesenchymal stem cells (BMSCs) and sufficient vascularization remain great challenges for the successful reconstruction of engineered adipose tissue. Here, the bioactive effects of silicon (Si) ions… read more here.
Keywords: angiogenesis; adipogenic differentiation; tissue; adipose tissue ... See more keywords
Long‐Term Imaging of Wound Angiogenesis with Large Scale Optoacoustic Microscopy
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DOI: 10.1002/advs.202004226
Abstract: Abstract Wound healing is a well‐coordinated process, necessitating efficient formation of new blood vessels. Vascularization defects are therefore a major risk factor for chronic, non‐healing wounds. The dynamics of mammalian tissue revascularization, vessel maturation, and… read more here.
Keywords: large scale; wound angiogenesis; angiogenesis; microscopy ... See more keywords
DEPDC1B Promotes Melanoma Angiogenesis and Metastasis through Sequestration of Ubiquitin Ligase CDC16 to Stabilize Secreted SCUBE3
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DOI: 10.1002/advs.202105226
Abstract: The ability of melanoma to acquire metastasis through the induction of angiogenesis is one of the major causes of skin cancer death. Here, it is found that high transcript levels of DEP domain containing 1B… read more here.
Keywords: metastasis; ubiquitin ligase; depdc1b; scube3 ... See more keywords
Effects of RhoC downregulation on the angiogenesis characteristics of myeloma vascular endothelial cells
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DOI: 10.1002/cam4.2208
Abstract: Tumor angiogenesis plays an important role in disease progression, and RhoC has been previously found to be expressed in vascular endothelial cells (VECs); however, its role in tumor angiogenesis requires clarification. This study aimed to… read more here.
Keywords: angiogenesis; rhoc downregulation; vascular endothelial; endothelial cells ... See more keywords
Targeting exosomes enveloped EBV-miR-BART1-5p-antagomiRs for NPC therapy through both anti-vasculogenic mimicry and anti-angiogenesis.
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DOI: 10.1002/cam4.5941
Abstract: BACKGROUND Nasopharyngeal carcinoma (NPC) is a type of head and neck cancer with high incidence in China. The molecular mechanisms of vasculogenic mimicry (VM) and angiogenesis are not fully elucidated in NPC. More specially, it… read more here.
Keywords: bart1; ebv mir; anti; angiogenesis ... See more keywords
Self‐Assembled DNA Nanocages Promote Cell Migration and Differentiation of Human Umbilical Vein Endothelial Cells **
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DOI: 10.1002/cbic.202200634
Abstract: DNA nanocages have been explored for abilities to influence cellular behavior and functions. Recent times have seen the development of new emergent functionalities of DNA nanodevices as a class of biomaterials with an immense capacity… read more here.
Keywords: cell; dna; human umbilical; differentiation human ... See more keywords
OGR1 mediates the inhibitory effects of acidic environment on proliferation and angiogenesis of endothelial progenitor cells
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DOI: 10.1002/cbin.11179
Abstract: Ovarian cancer G‐protein‐coupled receptor 1 (OGR1), an acid‐sensitive receptor, plays a key proton‐sensing role through stimulation of inositol phosphate formation. Avascular necrosis of the femoral head is characterized by apoptosis of bone cells mainly resulting… read more here.
Keywords: angiogenesis; ogr1; acidic environment; proliferation ... See more keywords