DNA aptamer immobilized hydroxyapatite for enhancing angiogenesis and bone regeneration.
Sign Up to like & getrecommendations! Published in 2019 at "Acta biomaterialia"
DOI: 10.1016/j.actbio.2019.08.047
Abstract: In this study, we developed aptamer-conjugated hydroxyapatite (Apt-HA) that promotes bone regeneration and angiogenesis. The 3R02 bivalent aptamer specific to vascular endothelial growth factor (VEGF) was grafted to the hydroxyapatite (HA) surface. Apt-HA was tested… read more here.
Keywords: bone; dna aptamer; angiogenesis bone; bone regeneration ... See more keywords
Coaxially fabricated polylactic acid electrospun nanofibrous scaffold for sequential release of tauroursodeoxycholic acid and bone morphogenic protein2 to stimulate angiogenesis and bone regeneration
Sign Up to like & getrecommendations! Published in 2020 at "Chemical Engineering Journal"
DOI: 10.1016/j.cej.2019.123470
Abstract: Abstract Angiogenesis and bone formation are closely related process in skeletal development and fracture healing. Angiogenic growth factors are predominantly expressed during the early phase in bone regeneration. Recently, chemical chaperone tauroursodeoxycholic acid (TUDCA) has… read more here.
Keywords: bone regeneration; angiogenesis bone; bone; acid ... See more keywords