Melatonin as an angiogenesis inhibitor to combat cancer: Mechanistic evidence
Sign Up to like & getrecommendations! Published in 2017 at "Toxicology and Applied Pharmacology"
DOI: 10.1016/j.taap.2017.09.022
Abstract: ABSTRACT Melatonin, a pineal indolamine, participates in different body functions and is shown to possess diverse biological activities such as anti‐tumor action. Angiogenesis inhibition is one of the mechanisms by which melatonin exerts its oncostatic… read more here.
Keywords: angiogenesis; angiogenesis inhibitor; cancer; hif agr ... See more keywords
Differential effects of cyclo-oxygenase 1 and 2 inhibition on angiogenesis inhibitor-induced hypertension and kidney damage.
Sign Up to like & getrecommendations! Published in 2022 at "Clinical science"
DOI: 10.1042/cs20220182
Abstract: Vascular endothelial growth factor antagonism with angiogenesis inhibitors in cancer patients induces a "preeclampsia-like" syndrome including hypertension, proteinuria and elevated endothelin (ET)-1. Cyclo-oxygenase (COX) inhibition with aspirin is known to prevent the onset of preeclampsia… read more here.
Keywords: induced hypertension; inhibitor induced; angiogenesis; angiogenesis inhibitor ... See more keywords
Efficacy and safety of angiogenesis inhibitors in melanoma: a meta-analysis of seven randomized controlled trials
Sign Up to like & getrecommendations! Published in 2022 at "Melanoma Research"
DOI: 10.1097/cmr.0000000000000812
Abstract: Little is known about the efficacy and safety of angiogenesis inhibitor therapy in patients with melanoma. The objective of this study was to assess the possible benefits and harms of angiogenesis inhibitor therapy in patients… read more here.
Keywords: efficacy safety; inhibitor therapy; angiogenesis inhibitor;
Study of siRNA Delivery via Polymeric Nanoparticles in Combination with Angiogenesis Inhibitor for The Treatment of AFP-Related Liver Cancer
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms232012666
Abstract: Angiogenesis inhibitor drugs have been explored as important pharmacological agents for cancer therapy, including hepatocellular carcinoma. These agents have several drawbacks, such as drug resistance, nonspecific toxicity, and systemic side effects. Therefore, combination therapy of… read more here.
Keywords: combination; treatment; afp sirna; angiogenesis inhibitor ... See more keywords