Angiogenin production in response to hypoxia and l-mimosine in periodontal fibroblasts.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of periodontology"
DOI: 10.1002/jper.18-0172
Abstract: BACKGROUND A major mediator of angiogenesis is angiogenin, which is expressed in the early phase of healing in oral tissue engineering strategies. It is unclear how angiogenin is regulated in the periodontal tissue. The objective… read more here.
Keywords: angiogenin; response hypoxia; hypoxia; mimosine ... See more keywords
The secretion of the angiogenic and neurotrophic factor angiogenin is COPII and microtubule dependent.
Sign Up to like & getrecommendations! Published in 2019 at "Experimental cell research"
DOI: 10.1016/j.yexcr.2019.05.025
Abstract: The RNaseA superfamily member Angiogenin (ANG) is a secreted protein involved in neovascularization, cell proliferation and stress response. Dysregulation of ANG expression is found in many cancers with poor prognosis and mutations in ANG are… read more here.
Keywords: secretion; angiogenin; microtubule dependent; cell ... See more keywords
Osteoclasts protect bone blood vessels against senescence through the angiogenin/plexin-B2 axis
Sign Up to like & getrecommendations! Published in 2021 at "Nature Communications"
DOI: 10.1038/s41467-021-22131-1
Abstract: Synthetic glucocorticoids (GCs), one of the most effective treatments for chronic inflammatory and autoimmune conditions in children, have adverse effects on the growing skeleton. GCs inhibit angiogenesis in growing bone, but the underlying mechanisms remain… read more here.
Keywords: angiogenin; endothelial cell; senescence; bone ... See more keywords
Human angiogenin is a potent cytotoxin in the absence of ribonuclease inhibitor.
Sign Up to like & getrecommendations! Published in 2018 at "RNA"
DOI: 10.1261/rna.065516.117
Abstract: Angiogenin (ANG) is a secretory ribonuclease that promotes the proliferation of endothelial cells, leading to angiogenesis. This function relies on its ribonucleolytic activity, which is low for simple RNA substrates. Upon entry into the cytosol,… read more here.
Keywords: potent cytotoxin; ribonuclease; angiogenin; ribonuclease inhibitor ... See more keywords
Urinary Angiogenin Reflects the Magnitude of Kidney Injury at the Infrahistologic Level.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of the American Society of Nephrology : JASN"
DOI: 10.1681/asn.2016020218
Abstract: The ribonuclease angiogenin is a component of the mammalian stress response that is secreted by renal epithelial cells on activation of the inositol-requiring enzyme 1α (IRE1α)-active spliced X-box binding protein 1 (sXBP1) axis and instrumental… read more here.
Keywords: kidney injury; reflects magnitude; urinary angiogenin; angiogenin ... See more keywords
Characterization and Function of the Interaction of Angiogenin With Alpha-Actinin 2
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Molecular Biosciences"
DOI: 10.3389/fmolb.2022.837971
Abstract: Angiogenin (ANG) is the first human tumor-derived angiogenic protein, which can promote angiogenesis and tumor growth. In a previous study, we identified alpha-actinin 2 (ACTN2), a cytoskeletal protein, as a direct interacting protein with angiogenin.… read more here.
Keywords: interaction; alpha actinin; actn2; angiogenin ... See more keywords