Triglyceride-derived fatty acids reduce autophagy in a model of retinal angiomatous proliferation.
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DOI: 10.1172/jci.insight.154174
Abstract: Dyslipidemia and autophagy have been implicated in the pathogenesis of blinding neovascular age-related macular degeneration (NV-AMD). Very low-density lipoprotein receptor (VLDLR), expressed in photoreceptors with a high metabolic rate, facilitates the uptake of triglyceride-derived fatty… read more here.
Keywords: derived fatty; angiomatous proliferation; triglyceride derived; retinal angiomatous ... See more keywords
Transcriptional and Distributional Profiling of Microglia in Retinal Angiomatous Proliferation
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DOI: 10.3390/ijms23073443
Abstract: Macular neovascularization type 3, formerly known as retinal angiomatous proliferation (RAP), is a hallmark of age-related macular degeneration and is associated with an accumulation of myeloid cells, such as microglia (MG) and infiltrating blood-derived macrophages… read more here.
Keywords: proliferation; retinal angiomatous; angiomatous proliferation; myeloid cell ... See more keywords