Angiopoietin-2 as a Prognostic Factor in Patients with Incurable Stage IV Colorectal Cancer
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Gastrointestinal Cancer"
DOI: 10.1007/s12029-020-00392-1
Abstract: Purpose Angiopoietin (Ang), a ligand of the endothelium-specific receptor Tie-2 system, is associated with tumor growth and progression that depend on angiogenesis. The present study aimed to investigate the predictive potential of angiopoietin factors in… read more here.
Keywords: incurable stage; stage colorectal; colorectal cancer; ang ... See more keywords
Angiopoietin-1 protects against endotoxin-induced neonatal lung injury and alveolar simplification in mice
Sign Up to like & getrecommendations! Published in 2021 at "Pediatric Research"
DOI: 10.1038/s41390-021-01544-0
Abstract: Sepsis in premature newborns is a risk factor for bronchopulmonary dysplasia (BPD), but underlying mechanisms of lung injury remain unclear. Aberrant expression of endothelial cell (EC) angiopoietin 2 (ANGPT2) disrupts angiopoietin 1 (ANGPT1)/TIE2-mediated endothelial quiescence,… read more here.
Keywords: sepsis; angiopoietin; lung injury; injury ... See more keywords
Inflammatory, fibrotic and endothelial biomarker profiles in COVID-19 patients during and following hospitalization
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DOI: 10.1038/s41598-025-09245-y
Abstract: Survivors of severe COVID-19 often suffer from long-term respiratory issues, but the molecular drivers of this damage remain unclear. This study explored the dynamics of inflammatory, fibrotic, and endothelial biomarkers in hospitalized COVID-19 patients. Plasma… read more here.
Keywords: covid patients; angiopoietin; fibrotic endothelial; inflammatory fibrotic ... See more keywords
Arsenic trioxide inhibits angiogenesis of hepatocellular carcinoma after insufficient radiofrequency ablation via blocking paracrine angiopoietin-1 and angiopoietin-2
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Hyperthermia"
DOI: 10.1080/02656736.2022.2093995
Abstract: Abstract Objectives Angiogenesis occurs during tumor progression of hepatocellular carcinoma (HCC) after insufficient radiofrequency ablation (RFA). Arsenic trioxide (ATO) shows promising therapeutic potential in advanced HCC. Whether ATO regulates angiogenesis and can be used to… read more here.
Keywords: angiopoietin; hcc insufficient; ato; rfa ... See more keywords
The effect of external counterpulsation on angiopoietin-1 and angiopoietin-2 levels in nondiabetic patients with refractory angina
Sign Up to like & getrecommendations! Published in 2023 at "European Journal of Preventive Cardiology"
DOI: 10.1093/eurjpc/zwad125.092
Abstract: Type of funding sources: Public grant(s) – National budget only. Main funding source(s): National Health Research and Development of the Ministry of Health of Indonesia. External counterpulsation (ECP) is a noninvasive therapy that employs external… read more here.
Keywords: angiopoietin; patients refractory; nondiabetic patients; ecp ... See more keywords
13: RECOMBINANT ANGIOPOIETIN 1 PROTECTS AGAINST LPS-INDUCED INFLAMMATION IN THE DEVELOPING MURINE LUNG
Sign Up to like & getrecommendations! Published in 2020 at "Critical Care Medicine"
DOI: 10.1097/01.ccm.0000618552.98706.b2
Abstract: Introduction/Hypothesis: Sepsis-induced acute lung injury (ALI) in premature newborns is a risk factor for bronchopulmonary dysplasia (BPD). Angiopoietins are vascular growth factors that regulate endothelial homeostasis and inflammation. During sepsis and ALI, angiopoietin 2 (ANGPT2)… read more here.
Keywords: sepsis; lung; bpd; angiopoietin ... See more keywords
Temporal Dysregulation of the Angiopoietin-2/-1 Ratio After Trauma and Associations With Injury Characteristics and Outcomes.
Sign Up to like & getrecommendations! Published in 2020 at "Shock"
DOI: 10.1097/shk.0000000000001597
Abstract: Traumatic injury and hemorrhagic shock result in endothelial cell activation and vascular dysfunction that, if not corrected, can propagate multiorgan failure. Angiopoietin-1 and angiopoietin-2 are important regulators of endothelial cell function, and the ratio of… read more here.
Keywords: angiopoietin ratios; ratio; angiopoietin; dysregulation ... See more keywords
Angiopoietin‐2 and angiopoietin‐like 4 protein provide prognostic information in patients with suspected acute coronary syndrome
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Internal Medicine"
DOI: 10.1111/joim.13339
Abstract: Plasma levels of angiopoietin‐2 (ANGPT2) and angiopoietin‐like 4 protein (ANGPTL4) reflect different pathophysiological aspects of cardiovascular disease. We evaluated their association with outcome in a hospitalized Norwegian patient cohort (n = 871) with suspected acute… read more here.
Keywords: suspected acute; like protein; acute coronary; angiopoietin ... See more keywords
FRI0275 HIGH ANGIOPOIETIN-2 LEVELS ASSOCIATE WITH ARTERIAL INFLAMMATION AND LONG-TERM GLUCOCORTICOID REQUIREMENT IN POLYMYALGIA RHEUMATICA
Sign Up to like & getrecommendations! Published in 2019 at "Annals of the Rheumatic Diseases"
DOI: 10.1136/annrheumdis-2019-eular.5394
Abstract: Background: Polymyalgia rheumatica (PMR) frequently co-occurs with giant cell arteritis (GCA). So far, a simple biomarker for detecting concomitant arterial inflammation in PMR patients is lacking. Furthermore, biomarkers predicting disease course in PMR are awaited.… read more here.
Keywords: none declared; polymyalgia rheumatica; pmr patients; pmr ... See more keywords
Increased Angiopoietin-1 and -2 levels in human vitreous are associated with proliferative diabetic retinopathy
Sign Up to like & getrecommendations! Published in 2023 at "PLOS ONE"
DOI: 10.1371/journal.pone.0280488
Abstract: Background Diabetic retinopathy is a frequent complication of diabetes mellitus and a leading cause of blindness in adults. The objective of this study was to elucidate the diabetic retinopathy pathophysiology in more detail by comparing… read more here.
Keywords: angiopoietin; retinopathy; human vitreous; correlation ... See more keywords
Ascending Vasa Recta Are Angiopoietin/Tie2-Dependent Lymphatic-Like Vessels.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of the American Society of Nephrology : JASN"
DOI: 10.1681/asn.2017090962
Abstract: Urinary concentrating ability is central to mammalian water balance and depends on a medullary osmotic gradient generated by a countercurrent multiplication mechanism. Medullary hyperosmolarity is protected from washout by countercurrent exchange and efficient removal of… read more here.
Keywords: angiopoietin tie2; fluid; ascending vasa; angiopoietin ... See more keywords