Temporal Dysregulation of the Angiopoietin-2/-1 Ratio After Trauma and Associations With Injury Characteristics and Outcomes.
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DOI: 10.1097/shk.0000000000001597
Abstract: Traumatic injury and hemorrhagic shock result in endothelial cell activation and vascular dysfunction that, if not corrected, can propagate multiorgan failure. Angiopoietin-1 and angiopoietin-2 are important regulators of endothelial cell function, and the ratio of… read more here.
Keywords: angiopoietin ratios; ratio; angiopoietin; dysregulation ... See more keywords
Microcirculatory perfusion disturbances following cardiac surgery with cardiopulmonary bypass are associated with in vitro endothelial hyperpermeability and increased angiopoietin-2 levels
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DOI: 10.1186/s13054-019-2418-5
Abstract: BackgroundEndothelial hyperpermeability following cardiopulmonary bypass (CPB) contributes to microcirculatory perfusion disturbances and postoperative complications after cardiac surgery. We investigated the postoperative course of renal and pulmonary endothelial barrier function and the association with microcirculatory perfusion… read more here.
Keywords: microcirculatory perfusion; angiopoietin levels; endothelial barrier; perfusion ... See more keywords
Prognostic significance of the angiopoietin-2 for early prediction of septic shock in severe sepsis patients
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DOI: 10.2144/fsoa-2022-0077
Abstract: Aim The current study investigated the plasma levels of angiopoietin-1/-2 and their association with clinical outcomes of sepsis. Methods Angiopoietin-1 and -2 levels were quantified in plasma from 105 patients with severe sepsis by ELISA.… read more here.
Keywords: sepsis; angiopoietin levels; severe sepsis; septic shock ... See more keywords