Association of New Use of Antihypertensives That Stimulate vs Inhibit Type 2 and 4 Angiotensin II Receptors With Dementia Among Medicare Beneficiaries
Sign Up to like & getrecommendations! Published in 2023 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2022.49370
Abstract: Key Points Question Is initiation of antihypertensive medications that stimulate vs inhibit type 2 and 4 angiotensin II receptors associated with a lower risk of dementia? Findings In this cohort study of 57 773 Medicare beneficiaries,… read more here.
Keywords: type angiotensin; inhibit type; stimulate inhibit; angiotensin receptors ... See more keywords
Non-radioactive binding assay for bradykinin and angiotensin receptors.
Sign Up to like & getrecommendations! Published in 2019 at "Methods in cell biology"
DOI: 10.1016/bs.mcb.2018.08.002
Abstract: G protein-coupled receptors (GPCRs) are the largest family of membrane protein playing an important role in cellular signal transduction. GPCRs interact with different molecules acting as ligands capable to trigger responses on signaling pathway. Those… read more here.
Keywords: bradykinin angiotensin; binding assay; assay bradykinin; angiotensin receptors ... See more keywords
Structural Basis for Selectivity and Diversity in Angiotensin II Receptors
Sign Up to like & getrecommendations! Published in 2017 at "Nature"
DOI: 10.1038/nature22035
Abstract: The angiotensin II receptors AT1R and AT2R serve as key components of the renin–angiotensin–aldosterone system. AT1R has a central role in the regulation of blood pressure, but the function of AT2R is unclear and it… read more here.
Keywords: basis selectivity; angiotensin receptors; structural basis; selectivity ... See more keywords
Angiotensin receptors - affinitiy and beyond.
Sign Up to like & getrecommendations! Published in 2022 at "Clinical science"
DOI: 10.1042/cs20220024
Abstract: This commentary on the article "Relative affinity of angiotensin peptides and novel ligands at AT1 and AT2 receptors" by Sanja Bosnyak et al. (Clini. Sci. (Lond.) (2011) 121(7): 297-303. https://doi.org/10.1042/CS20110036) summarises the main findings of… read more here.
Keywords: angiotensin; receptors affinitiy; angiotensin receptors; affinitiy beyond ... See more keywords
Expression and localization of the AT1 and AT2 angiotensin II receptors and α1A and α1D adrenergic receptors in aorta of hypertensive and diabetic rats
Sign Up to like & getrecommendations! Published in 2017 at "Clinical and Experimental Hypertension"
DOI: 10.1080/10641963.2016.1200610
Abstract: ABSTRACT Hypertension and diabetes are multifactorial diseases that frequently coexist and exacerbate each another. During the development of diabetes, the impairment of noradrenergic and renin-angiotensin systems has been reported in the response mediated by α1-AR… read more here.
Keywords: at1 at2; adrenergic receptors; angiotensin; angiotensin receptors ... See more keywords
Association of Polymorphisms in the Genes of Angiotensinogen and Angiotensin Receptors With Risk for Basal Cell Carcinoma
Sign Up to like & getrecommendations! Published in 2019 at "AntiCancer Research"
DOI: 10.21873/anticanres.13745
Abstract: Background/Aim: Basal cell carcinoma (BCC) has been genetically associated with an increased expression of angiotensin-converting enzyme (ACE), an important factor of the renin–angiotensin system which produces vasoconstrictor angiotensin II. Other factors of this system include… read more here.
Keywords: angiotensin receptors; cell carcinoma; basal cell; angiotensin ... See more keywords
Angiotensin Receptors Heterodimerization and Trafficking: How Much Do They Influence Their Biological Function?
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2020.01179
Abstract: G-protein–coupled receptors (GPCRs) are targets for around one third of currently approved and clinical prescribed drugs and represent the largest and most structurally diverse family of transmembrane signaling proteins, with almost 1000 members identified in… read more here.
Keywords: receptors heterodimerization; heterodimerization trafficking; biological function; function ... See more keywords