A pilot study of alterations in oxidized angiotensinogen and antioxidants in pre-eclamptic pregnancy
Sign Up to like & getrecommendations! Published in 2020 at "Scientific Reports"
DOI: 10.1038/s41598-020-58930-7
Abstract: The oxidation status of angiotensinogen (AGT) may have a critical role in pre-eclampsia. We used a validated, quantitative, mass spectrometry-based method to measure the oxidized and total AGT levels in plasma of pre-eclamptic women (n = 17),… read more here.
Keywords: pre eclampsia; pre eclamptic; oxidized agt; angiotensinogen ... See more keywords
Fifty years of research on the brain renin-angiotensin system: what have we learned?
Sign Up to like & getrecommendations! Published in 2021 at "Clinical science"
DOI: 10.1042/cs20210579
Abstract: Although the existence of a brain renin-angiotensin system (RAS) had been proposed five decades ago, we still struggle to understand how it functions. The main reason for this is the virtual lack of renin at… read more here.
Keywords: renin; renin angiotensin; angiotensinogen; brain renin ... See more keywords
A4480 Chronic treatment with a SGLT2 inhibitor does not activate systemic and intrarenal renin-angiotensin system in CKD rats
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Hypertension"
DOI: 10.1097/01.hjh.0000548058.43048.be
Abstract: Objectives: We aimed to examine the effects of a sodium glucose co-transporter 2 (SGLT2) inhibitor on systemic and intrarenal renin-angiotensin system (RAS) activity in subtotally nephrectomized non-diabetic rats, a model of chronic kidney disease (CKD).… read more here.
Keywords: systemic intrarenal; angiotensin; sglt2 inhibitor; angiotensinogen ... See more keywords
THU0018 Angiotensinogen as a marker of injury in lupus nephritis
Sign Up to like & getrecommendations! Published in 2017 at "Annals of the Rheumatic Diseases"
DOI: 10.1136/annrheumdis-2017-eular.6760
Abstract: Background Lupus Nephritis (LN) is one of the most severe forms of systemic lupus erythematosus (SLE) (1). Angiotensinogen (AGT) gene encodes the only glycoprotein known to be a precursor of the vasopresor angiotensin II (Ang… read more here.
Keywords: agt gene; angiotensinogen; class; lupus nephritis ... See more keywords
Two Amino Acids Proximate to the Renin Cleavage Site of Human Angiotensinogen Do Not Affect Blood Pressure and Atherosclerosis in Mice—Brief Report
Sign Up to like & getrecommendations! Published in 2020 at "Arteriosclerosis, Thrombosis, and Vascular Biology"
DOI: 10.1161/atvbaha.120.314048
Abstract: Supplemental Digital Content is available in the text. Objective: Renin cleavage of angiotensinogen has species specificity. As the residues at positions 11 and 12 are different between human angiotensinogen and mouse angiotensinogen, we determined whether… read more here.
Keywords: mice; blood pressure; mouse angiotensinogen; hepagt mice ... See more keywords
The Urinary Angiotensinogen to Urinary Albumin Ratio Reflects Whether the Renin-angiotensin System in the Kidney Is Activated due to Filtration of Plasma Angiotensinogen through the Damaged Glomeruli or the Production of Angiotensinogen in the Proximal Tubules
Sign Up to like & getrecommendations! Published in 2019 at "Internal Medicine"
DOI: 10.2169/internalmedicine.3624-19
Abstract: Objective Urinary angiotensinogen (AGT) is a surrogate marker for intrarenal renin-angiotensin system (RAS) activity that plays an important role in the development of renal damage. Urinary AGT levels are determined by the filtration of plasma… read more here.
Keywords: urinary agt; production; angiotensinogen; urinary albumin ... See more keywords
Polymorphism rs7079 in miR-31/-584 Binding Site in Angiotensinogen Gene Associates with Earlier Onset of Coronary Artery Disease in Central European Population
Sign Up to like & getrecommendations! Published in 2022 at "Genes"
DOI: 10.3390/genes13111981
Abstract: Angiotensinogen (AGT) represents a key component of the renin–angiotensin–aldosterone system (RAAS). Polymorphisms in the 3′ untranslated region (3′UTR) of the AGT gene may alter miRNA binding and cause disbalance in the RAAS. Within this study,… read more here.
Keywords: gene; coronary artery; angiotensinogen; polymorphism rs7079 ... See more keywords
Genetic Polymorphism in Angiotensinogen and Its Association with Cardiometabolic Diseases
Sign Up to like & getrecommendations! Published in 2022 at "Metabolites"
DOI: 10.3390/metabo12121291
Abstract: Angiotensinogen (AGT) is one of the most significant enzymes of the renin-angiotensin-aldosterone system (RAAS) which is involved in the regulation and maintenance of blood pressure. AGT is involved in the production of angiotensin I which… read more here.
Keywords: angiotensinogen; polymorphism; genetic polymorphism; variants agt ... See more keywords