Angler Peptides: Macrocyclic Conjugates Inhibit p53:MDM2/X Interactions and Activate Apoptosis in Cancer Cells.
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DOI: 10.1021/acschembio.0c00988
Abstract: Peptides are being developed as targeted anticancer drugs to modulate cytosolic protein-protein interactions involved in cancer progression. However, their use as therapeutics is often limited by their low cell membrane permeation and/or inability to reach… read more here.
Keywords: cancer; cell; p53 mdm2; angler peptides ... See more keywords