Angiopoietin-like protein 2 deficiency promotes periodontal inflammation and alveolar bone loss.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of periodontology"
DOI: 10.1002/jper.21-0290
Abstract: BACKGROUND Human periodontitis is a highly prevalent inflammatory disease that leads to connective tissue degradation, alveolar bone resorption, and tooth loss. Angiopoietin-like 2 (ANGPTL2) regulates chronic inflammation in various diseases and is functionally involved in… read more here.
Keywords: bone loss; angptl2; alveolar bone; periodontitis ... See more keywords
Foxc2 Alleviates Ox-LDL-Induced Lipid Accumulation, Inflammation, and Apoptosis of Macrophage via Regulating the Expression of Angptl2
Sign Up to like & getrecommendations! Published in 2020 at "Inflammation"
DOI: 10.1007/s10753-020-01217-w
Abstract: The present study aimed to investigate the role of Forkhead box protein C2 (Foxc2) in oxidized low-density lipoprotein (ox-LDL)-induced macrophages and identify the potential mechanisms. RAW264.7 cells, the murine macrophage cell line, were stimulated by… read more here.
Keywords: apoptosis; inflammation; angptl2; expression angptl2 ... See more keywords
Angiopoietin-like 2 is a potential biomarker for diabetic foot patients
Sign Up to like & getrecommendations! Published in 2020 at "BMC Endocrine Disorders"
DOI: 10.1186/s12902-020-00657-7
Abstract: Background Circulating angiopoietin-like 2 ( ANGPTL2) protein levels are known to be significantly increased in numerous chronic inflammatory diseases and are associated with the diagnosis and/or prognosis of cardiovascular diseases, diabetes, chronic kidney disease, and… read more here.
Keywords: like potential; dfus; angptl2; angiopoietin like ... See more keywords
2214-LB: Adipocyte-Derived Exosomal ANGPTL2 Mediates Pancreatic Beta Cell Dysfunction under Lipotoxic Conditions by Activating the EIF2α/ATF4/CHOP Pathway
Sign Up to like & getrecommendations! Published in 2025 at "Diabetes"
DOI: 10.2337/db25-2214-lb
Abstract: Introduction and Objective: Obesity contributes significantly to type 2 diabetes by disrupting crosstalk between adipose tissue and beta cells. This study explores how adipocyte-derived exosomes enriched in angiopoietin-like protein 2 (ANGPTL2) mediate beta cell dysfunction… read more here.
Keywords: none; cell dysfunction; beta; beta cell ... See more keywords