ANGPTL7 is transcriptionally regulated by SP1 and modulates glucocorticoid-induced cross-linked actin networks in trabecular meshwork cells via the RhoA/ROCK pathway
Sign Up to like & getrecommendations! Published in 2022 at "Cell Death Discovery"
DOI: 10.1038/s41420-022-00847-3
Abstract: Glaucoma is one of the leading causes of worldwide irreversible blindness. Lowering elevated intraocular pressure (IOP) is currently the only effective approach for controlling the progress of glaucoma. Angiopoietin-like 7 (ANGPTL7) takes a key part… read more here.
Keywords: clan formation; angptl7; rhoa rock; formation ... See more keywords
2069-LB: ANGPTL7 Promotes Oxidative Stress and Inflammatory Response in HepG2 Cells via Targeting the STAT3-iNOS, COX-2 Signaling Pathway
Sign Up to like & getrecommendations! Published in 2024 at "Diabetes"
DOI: 10.2337/db24-2069-lb
Abstract: Objective: Elevated hepatocyte oxidative stress and inflammation may trigger lipid accumulation and promote the formation of NAFLD. As a new member of the ANGPTL family, ANGPTL7 plays an important role in inflammatory responses, angiogenesis and… read more here.
Keywords: stat3 inos; stress; oxidative stress; hepg2 cells ... See more keywords
Increased plasma ANGPTL7 levels with increased obstructive sleep apnea severity
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Endocrinology"
DOI: 10.3389/fendo.2022.922425
Abstract: Background Weight-loss surgery is one of the recommended methods for treating obstructive sleep apnea (OSA) in obese patients. While weight reduction is critical to relieve symptoms of OSA, the biochemical factors involved in post-surgery improvement… read more here.
Keywords: surgery; osa; sleep apnea; severity ... See more keywords