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   Articles with "angptl8" as a keyword



Abstract Or121: Functional dissection of ANGPTL3

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recommendations! Published in 2025 at "Arteriosclerosis, Thrombosis, and Vascular Biology"

DOI: 10.1161/atv.45.suppl_1.or121

Abstract: Dyslipidemia is a risk factor for metabolic diseases, emphasizing the importance of regulating lipoprotein metabolism. Levels of lipoproteins are regulated, in part, by extracellular lipases including lipoprotein lipase (LPL) and endothelial lipase (EL). Angiopoietin-like-3 (ANGPTL3)… read more here.

Keywords: angptl8; residues angptl3; inhibition; lipase ... See more keywords

ANGPTL8 promotes adipogenic differentiation of mesenchymal stem cells: potential role in ectopic lipid deposition

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recommendations! Published in 2022 at "Frontiers in Endocrinology"

DOI: 10.3389/fendo.2022.927763

Abstract: Background Ectopic lipid deposition plays a promoting role in many chronic metabolic diseases. Abnormal adipogenic differentiation of mesenchymal stem cells (MSCs) is an important cause of lipid deposition in organs. Studies have shown that serum… read more here.

Keywords: angptl8; ectopic lipid; deposition; differentiation ... See more keywords

Angiopoietin-2 and Angiopoietin-like Proteins with a Prospective Role in Predicting Diabetic Nephropathy

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recommendations! Published in 2024 at "Biomedicines"

DOI: 10.3390/biomedicines12050949

Abstract: Angiopoietins are crucial growth factors for maintaining a healthy, functional endothelium. Patients with type 2 diabetes (T2D) exhibit significant levels of angiogenic markers, particularly Angiopoietin-2, which compromises endothelial integrity and is connected to symptoms of… read more here.

Keywords: angiopoietin like; angptl8; diabetic nephropathy; like proteins ... See more keywords
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Role of ANGPTL8 in NAFLD Improvement after Bariatric Surgery in Experimental and Human Obesity

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recommendations! Published in 2021 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms222312945

Abstract: Angiopoietin-like protein 8 (ANGPTL8) is an hepatokine altered in several metabolic conditions, such as obesity, type 2 diabetes, dyslipidemia and nonalcoholic fatty liver disease (NAFLD). We sought to explore whether ANGPTL8 is involved in NAFLD… read more here.

Keywords: bariatric surgery; surgery experimental; obesity; angptl8 ... See more keywords

Serum ANGPTL8 and ANGPTL3 as Predictors of Triglyceride Elevation in Adult Women

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recommendations! Published in 2022 at "Metabolites"

DOI: 10.3390/metabo12060539

Abstract: Angiopoietin-like proteins ANGPTL3 and ANGPTL8 have been shown to inhibit lipoprotein lipase, and thus regulate triglyceride level in the circulation. Whether the regulation of lipid metabolism by ANGPTLs is affected by the menopausal status remains… read more here.

Keywords: angptl8; menopausal status; triglyceride elevation; angptl3 ... See more keywords