Toward an Improved Understanding of Anhedonia.
Sign Up to like & getrecommendations! Published in 2019 at "JAMA psychiatry"
DOI: 10.1001/jamapsychiatry.2018.4600
Abstract: Anhedonia, the reduced ability to experience pleasure, has been critically implicated in a wide range of adolescent mental disorders and suicidal behaviors.1,2 Presently, medication as well as most first-line psychotherapeutic approaches do not sufficiently address… read more here.
Keywords: research; understanding anhedonia; toward improved; improved understanding ... See more keywords
Working memory training can improve anhedonia in college students with subsyndromal depressive symptoms.
Sign Up to like & getrecommendations! Published in 2019 at "PsyCh journal"
DOI: 10.1002/pchj.271
Abstract: Anhedonia is defined as deficits in experiencing everyday life pleasure. Empirical studies suggest that anhedonia and working memory (WM) share overlapping neural substrates. Although WM training has been shown to alleviate anhedonia in individuals with… read more here.
Keywords: college students; training; working memory; anhedonia ... See more keywords
Peer delivered services in mental health care in 2018: infancy or adolescence?
Sign Up to like & getrecommendations! Published in 2018 at "World Psychiatry"
DOI: 10.1002/wps.20530
Abstract: ing effect on reward processing. Studies examining the neural response to rewarding stimuli in schizophrenia suggest that second generation antipsychotics are associated with intact response to reward outcomes in the ventral striatum. Since individuals with… read more here.
Keywords: schizophrenia; high risk; individuals schizotypy; anhedonia ... See more keywords
Anhedonia in Posttraumatic Stress Disorder: Prevalence, Phenotypes, and Neural Circuitry.
Sign Up to like & getrecommendations! Published in 2021 at "Current topics in behavioral neurosciences"
DOI: 10.1007/7854_2021_292
Abstract: Anhedonia, the reduction of pleasure and reward-seeking behavior, is a transdiagnostic construct associated with a range of important health outcomes. As with other psychiatric disorders, anhedonia is a relatively common, though understudied, feature of posttraumatic… read more here.
Keywords: anhedonia; disorder; circuitry; posttraumatic stress ... See more keywords
Inflammation as a Pathophysiologic Pathway to Anhedonia: Mechanisms and Therapeutic Implications.
Sign Up to like & getrecommendations! Published in 2022 at "Current topics in behavioral neurosciences"
DOI: 10.1007/7854_2021_294
Abstract: Anhedonia, characterized by a lack of motivation, interest, or ability to experience pleasure, is a prominent symptom of depression and other psychiatric disorders and has been associated with poor response to standard therapies. One pathophysiologic… read more here.
Keywords: anhedonia; pathophysiologic pathway; anhedonia mechanisms; pathway anhedonia ... See more keywords
Mapping anticipatory anhedonia: an fMRI study
Sign Up to like & getrecommendations! Published in 2019 at "Brain Imaging and Behavior"
DOI: 10.1007/s11682-019-00084-w
Abstract: Anhedonia—broadly defined as loss of interest and/or an inability to experience pleasure—is an important feature of several psychiatric disorders. Research into the clinical presentation and neurobiology of this symptom has identified components related to motivation,… read more here.
Keywords: pleasure; anticipatory anhedonia; healthy controls; study ... See more keywords
A short-term longitudinal examination of the relations between depression, anhedonia, and self-injurious thoughts and behaviors in adults with a history of self-injury.
Sign Up to like & getrecommendations! Published in 2017 at "Comprehensive psychiatry"
DOI: 10.1016/j.comppsych.2016.11.013
Abstract: BACKGROUND Limited research has addressed the role of anhedonia in predicting suicidality and/or nonsuicidal self-injury (NSSI) in adults, despite evidence suggesting that loss of interest or pleasure may increase vulnerability for self-inflicted harm, even beyond… read more here.
Keywords: depression; suicidality; self injury; history ... See more keywords
Brain insulin resistance: A treatment target for cognitive impairment and anhedonia in depression
Sign Up to like & getrecommendations! Published in 2019 at "Experimental Neurology"
DOI: 10.1016/j.expneurol.2019.01.016
Abstract: &NA; Type 2 Diabetes Mellitus (T2DM) and Major Depressive Disorder (MDD) are leading causes of disability worldwide. Indeed, both are costly and burdensome diseases at both individual and socio‐economic levels. Notably, there are similar pathophysiological… read more here.
Keywords: insulin; anhedonia; brain insulin; insulin resistance ... See more keywords
Changes in symptoms of anhedonia in adults with major depressive or bipolar disorder receiving IV ketamine: Results from the Canadian Rapid Treatment Center of Excellence.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of affective disorders"
DOI: 10.1016/j.jad.2020.07.083
Abstract: BACKGROUND Anhedonia is a trans-diagnostic, multidimensional phenotype that mediates patient outcomes and suicidality. Convergent evidence suggests that ketamine may be effective in targeting measures of anhedonia in adults with treatment resistant depression (TRD). METHODS This… read more here.
Keywords: symptoms anhedonia; depression; treatment; severity ... See more keywords
Cortisol reactivity to stress predicts behavioral responsivity to reward moderation by sex, depression, and anhedonia.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of affective disorders"
DOI: 10.1016/j.jad.2021.05.126
Abstract: Depression is associated with blunted reactivity to acute stress, as well as blunted responsivity to rewards. However, the extent to which responses to stress are associated with responses to reward in individuals meeting criteria for… read more here.
Keywords: cortisol; depression; reactivity; stress ... See more keywords
Musical anhedonia after focal brain damage
Sign Up to like & getrecommendations! Published in 2017 at "Neuropsychologia"
DOI: 10.1016/j.neuropsychologia.2017.01.030
Abstract: &NA; People listen to music because it is pleasurable. However, there are individual differences in the reward value of music. At the extreme low end of this continuum, individuals who derive no pleasure from music… read more here.
Keywords: brain damage; anhedonia; focal brain; musical anhedonia ... See more keywords