QSAR and docking studies on Triazole Benzene Sulfonamides with human Carbonic anhydrase IX inhibitory activity
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Chemometrics"
DOI: 10.1002/cem.3189
Abstract: Cancer is the second leading cause of death worldwide, and breast cancer accounts for 2.09 million cases in the year 2018. Hypoxia‐related human carbonic anhydrase IX enzyme was found to play a key role in… read more here.
Keywords: carbonic anhydrase; anhydrase inhibitory; triazole benzene; human carbonic ... See more keywords
Investigation of carbonic anhydrase inhibitory potency of (Z/E)-alkyl N'-benzyl-N-(arylsulfonyl)-carbamimidothioates.
Sign Up to like & getrecommendations! Published in 2023 at "Future medicinal chemistry"
DOI: 10.4155/fmc-2022-0287
Abstract: Aim: Among 15 human (h) carbonic anhydrase (CA; EC 4.2.1.1) isoforms, two (hCA IX and XII) play important roles in the growth and survival of tumor cells, making them therapeutic targets for cancer treatment. This study… read more here.
Keywords: investigation carbonic; anhydrase inhibitory; carbonic anhydrase; hca xii ... See more keywords