Inhibition of Bacterial Carbonic Anhydrases as a Novel Approach to Escape Drug Resistance.
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DOI: 10.2174/1568026617666170104101058
Abstract: BACKGROUND Clinically used antibiotics act through one of these four mechanisms: cell wall biosynthesis inhibition, inhibition of protein biosynthesis, interference with DNA and RNA synthesis and the folate pathway. OBJECTIVE The metalloenzymes carbonic anhydrases (CAs,… read more here.
Keywords: carbonic anhydrases; bacterial carbonic; inhibition; drug ... See more keywords