Unexpected Biotransformation of the HDAC Inhibitor Vorinostat Yields Aniline-Containing Fungal Metabolites.
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DOI: 10.1021/acschembio.7b00268
Abstract: The diversity of genetically encoded small molecules produced by filamentous fungi remains largely unexplored, which makes these fungi an attractive source for the discovery of new compounds. However, accessing their full chemical repertoire under common… read more here.
Keywords: aniline containing; vorinostat; inhibitor vorinostat; hdac inhibitor ... See more keywords