Catalyst-Controlled Chemodivergent Reactivity of Vinyl Cyclopropanes: A Selective Approach toward Indoles and Aniline Derivatives.
Sign Up to like & getrecommendations! Published in 2022 at "Organic letters"
DOI: 10.1021/acs.orglett.2c03680
Abstract: Herein, we disclose a catalyst-controlled chemodivergent approach to access C2-substituted indoles and diverse aniline derivatives with good chemo- and stereoselectivity by employing vinylcyclopropanes (VCPs) as coupling partners via a tandem C-H/C-C activation/annulation strategy. The key… read more here.
Keywords: chemodivergent reactivity; aniline derivatives; controlled chemodivergent; catalyst controlled ... See more keywords
Asymmetric Synthesis of Triphenylmethanes via Organocatalytic Regio- and Enantioselective Friedel-Crafts Alkylation of Aniline Derivatives.
Sign Up to like & getrecommendations! Published in 2023 at "Organic letters"
DOI: 10.1021/acs.orglett.3c00370
Abstract: Herein, we described a highly regio- and enantioselective Friedel-Crafts alkylation of aniline derivatives with in situ generated ortho-quinone methides enabled by chiral phosphoric acid, furnishing a wide range of enantioenriched triarylmethanes bearing three similar benzene… read more here.
Keywords: crafts alkylation; friedel crafts; aniline derivatives; regio enantioselective ... See more keywords
Mechanistic Study of the Role of Substrate Steric Effects and Aniline Inhibition on the Bis(trineopentylphosphine)palladium(0)-Catalyzed Arylation of Aniline Derivatives
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DOI: 10.1021/acscatal.7b00024
Abstract: The mechanism of the bis(trineopentylphosphine)palladium(0) (Pd(PNp3)2)-catalyzed coupling of aryl halides and aniline derivatives was studied in an effort to understand the role of substrate steric effects on the reaction. Prior studies had shown that the… read more here.
Keywords: substrate steric; aniline derivatives; bis trineopentylphosphine; rate ... See more keywords
Functiaonalization of 2-(1-Cyclohexen-1-yl)aniline Derivatives
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DOI: 10.1134/s1070363219040030
Abstract: The reaction of 2-(1-cyclohexen-1-yl)aniline and -6-methylaniline with phthalic anhydride has afforded 2-(2-cyclohex-1-en-1-ylphenyl)- and 2-(2-cyclohex-1-en-1-ylphenyl)-6-methylphenyl)-1H-isoindole-1,3(2H)-diones. The reaction of the obtained isoindole-1,3-diones with bromine in dichloromethane in the presence of sodium bicarbonate has led to the formation… read more here.
Keywords: cyclohexen aniline; presence; reaction; methylphenyl isoindole ... See more keywords
Mechanistic Aspects of the Electrochemical Oxidation of Aliphatic Amines and Aniline Derivatives
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DOI: 10.3390/molecules28020471
Abstract: The electrochemical oxidation of amines is an essential alternative to the conventional chemical transformation that provides critical routes for synthesising and modifying a wide range of chemically useful molecules, including pharmaceuticals and agrochemicals. As a… read more here.
Keywords: electrochemical oxidation; oxidation; mechanistic aspects; aniline derivatives ... See more keywords