Synthesis of 1,5-Substituted Pyrrolidin-2-ones from Donor–Acceptor Cyclopropanes and Anilines/Benzylamines
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DOI: 10.3390/molecules27238468
Abstract: We developed a straightforward synthetic route to pharmacologically important 1,5-substituted pyrrolidin-2-ones from donor–acceptor cyclopropanes bearing an ester group as one of the acceptor substituents. This method includes a Lewis acid-catalyzed opening of the donor–acceptor cyclopropane… read more here.
Keywords: acceptor cyclopropanes; acceptor; chemistry; anilines benzylamines ... See more keywords