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Published in 2021 at "Bioorganic chemistry"
DOI: 10.1016/j.bioorg.2021.105359
Abstract: Malaria is a devastating disease caused by Plasmodium parasites. Emerging resistance against current antimalarial therapeutics has engendered the need to develop antimalarials with novel structural classes. We recently described the identification and initial optimization of…
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Keywords:
class;
asexual parasite;
parasite activity;
fast acting ... See more keywords
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Published in 2023 at "Molecules"
DOI: 10.3390/molecules28041712
Abstract: Pyrazole core represents a privilege scaffold in medicinal chemistry; a number of pyrazole compounds are endowed with various pharmacological activities in different therapeutic areas including antimalarial treatment. Supported by this evidence, a series of 5-anilino-3-(hetero)arylpyrazoles…
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Keywords:
anilino;
antimalarial activity;
activity tri;
tri tetra ... See more keywords