Exhaustive identification of conserved upstream open reading frames with potential translational regulatory functions from animal genomes
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DOI: 10.1038/s41598-020-73307-6
Abstract: Upstream open reading frames (uORFs) are present in the 5′-untranslated regions of many eukaryotic mRNAs, and some peptides encoded by these regions play important regulatory roles in controlling main ORF (mORF) translation. We previously developed… read more here.
Keywords: reading frames; animal genomes; upstream open; cpuorfs ... See more keywords
SYNPHONI: scale-free and phylogeny-aware reconstruction of synteny conservation and transformation across animal genomes
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DOI: 10.1093/bioinformatics/btac695
Abstract: Abstract Summary Current approaches detect conserved genomic order either at chromosomal (macrosynteny) or at subchromosomal scales (microsynteny). The latter generally requires collinearity and hard thresholds on syntenic region size, thus excluding a major proportion of… read more here.
Keywords: synteny conservation; animal genomes; conservation transformation;
The FAANG Data Portal: Global, Open-Access, “FAIR”, and Richly Validated Genotype to Phenotype Data for High-Quality Functional Annotation of Animal Genomes
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2021.639238
Abstract: The Functional Annotation of ANimal Genomes (FAANG) project is a worldwide coordinated action creating high-quality functional annotation of farmed and companion animal genomes. The generation of a rich genome-to-phenome resource and supporting informatic infrastructure advances… read more here.
Keywords: functional annotation; high quality; animal genomes; faang data ... See more keywords
Editorial: Functional Annotation of Animal Genomes
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2021.768626
Abstract: Agriculture Victoria, Agribio, Centre for AgriBiosciences, Bundoora, VIC, Australia, Avian Disease and Oncology Laboratory, Washington D.C., MI, United States, Paris-Saclay University, INRAE, AgroParisTech, GABI, Jouy-en-Josas, Jouy-en-Josas, France, Research Institute for Farm Animal Biology (FBN), Dummerstorf,… read more here.
Keywords: functional annotation; annotation animal; animal; united states ... See more keywords