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Published in 2020 at "PLoS ONE"
DOI: 10.1371/journal.pone.0235815
Abstract: Monoclonal antibodies (mAbs) for therapeutic applications should be as similar to native human antibodies as possible to minimize their immunogenicity in patients. Several transgenic animal platforms are available for the generation of fully human mAbs.…
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Keywords:
developability;
transgenic animal;
animal platforms;
platforms complementary ... See more keywords