Pyridylic anions are soft nucleophiles in the palladium-catalyzed C(sp3)–H allylation of 4-alkylpyridinesâ€
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DOI: 10.1039/d0sc03304a
Abstract: We report a mild palladium-catalyzed method for the selective allylation of 4-alkylpyridines in which highly basic pyridylic anions behave as soft nucleophiles. This method exploits alkylidene dihydropyridines, which are semi-stable intermediates readily formed using a… read more here.
Keywords: soft nucleophiles; palladium catalyzed; anions soft; allylation alkylpyridines ... See more keywords