ANKRD22 promotes glioma proliferation, migration, invasion, and epithelial-mesenchymal transition by upregulating E2F1-mediated MELK expression.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of neuropathology and experimental neurology"
DOI: 10.1093/jnen/nlad034
Abstract: Ankyrin repeat domain protein 22 (ANKRD22) has been implicated in various types of cancers but its expression and potential functions have not been investigated in gliomas. In this study, the high expression of ANKRD22 in… read more here.
Keywords: proliferation migration; migration invasion; ankrd22; expression ... See more keywords
ANKRD22 is a potential novel target for reversing the immunosuppressive effects of PMN-MDSCs in ovarian cancer
Sign Up to like & getrecommendations! Published in 2023 at "Journal for Immunotherapy of Cancer"
DOI: 10.1136/jitc-2022-005527
Abstract: Background Ovarian cancer is the deadliest type of malignant gynecological tumor. Polymorphonuclear myeloid-derived suppressor cells (PMN-MDSCs) are involved ovarian cancer and are closely related to adverse outcomes. However, the immunosuppressive mechanism of PMN-MDSCs remains elusive.… read more here.
Keywords: pmn mdscs; ovarian cancer; cancer; ankrd22 ... See more keywords
ANKRD22 is involved in the progression of prostate cancer
Sign Up to like & getrecommendations! Published in 2019 at "Oncology Letters"
DOI: 10.3892/ol.2019.10738
Abstract: Prostate cancer is a common malignant tumor in elderly men. As a novel metabolic-reprogramming molecule, the role of ankyrin repeat domain 22 (ANKRD22) in the tumorigenesis and progression of prostate cancer remains unknown. In the… read more here.
Keywords: cancer; progression prostate; ankrd22; prostate cancer ... See more keywords