Differential expression of circular RNAs in plasma exosomes from patients with ankylosing spondylitis
Sign Up to like & getrecommendations! Published in 2022 at "Cell Biology International"
DOI: 10.1002/cbin.11760
Abstract: Exosomes are being extensively studied as a source of valuable new biomarkers. The underlying mechanism of ankylosing spondylitis (AS) may include changes in the circular RNAs (circRNAs) of exosomes. However, there is a lack of… read more here.
Keywords: expressed circrnas; circular rnas; differentially expressed; exosomes patients ... See more keywords
Evaluation of the oral administration of α‐l‐guluronic acid on COX‐1 and COX‐2 gene expression profile in ankylosing spondylitis patients
Sign Up to like & getrecommendations! Published in 2020 at "Drug Development Research"
DOI: 10.1002/ddr.21756
Abstract: Ankylosing spondylitis (AS) is a chronic autoimmune arthritis disease with a genetic background, affecting the skeletal axis, sacroiliac, and peripheral joints. Nonsteroidal anti‐inflammatory drugs (NSAIDs) are the first‐line treatment for AS to alleviate the inflammation… read more here.
Keywords: cox; cox cox; gene expression; ankylosing spondylitis ... See more keywords
BMP2 variants in the risk of ankylosing spondylitis
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.29563
Abstract: The purpose of the study was to explore the genetic effects of bone morphogenetic protein (BMP2) polymorphisms on the susceptibility to ankylosing spondylitis (AS) in Chinese Han population. The case‐control study included 120 AS cases… read more here.
Keywords: ankylosing spondylitis; control; bmp2 variants; bmp2 ... See more keywords
The association of NLRP3 and TNFRSF1A polymorphisms with risk of ankylosing spondylitis and treatment efficacy of etanercept
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Clinical Laboratory Analysis"
DOI: 10.1002/jcla.22138
Abstract: To discover how NLRP3 and TNFRSF1A polymorphisms affect the efficacy of traditional medicine and etanercept for ankylosing spondylitis (AS) patients. read more here.
Keywords: ankylosing spondylitis; tnfrsf1a polymorphisms; nlrp3 tnfrsf1a; polymorphisms risk ... See more keywords
PBMC CDC42 reveals the disease activity and treatment efficacy of TNF inhibitor in patients with ankylosing spondylitis
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Clinical Laboratory Analysis"
DOI: 10.1002/jcla.24267
Abstract: Cell division cycle 42 (CDC42) regulates the polarization of M2 macrophage and maintains the T cell homeostasis, to participate in multiple autoimmune diseases, while its clinical involvement in ankylosing spondylitis (AS) remains unclear. Hence, the… read more here.
Keywords: tnf inhibitor; treatment; cdc42; ankylosing spondylitis ... See more keywords
MALT1 positively relates to Th17 cells, inflammation/activity degree, and its decrement along with treatment reflects TNF inhibitor response in ankylosing spondylitis patients
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Clinical Laboratory Analysis"
DOI: 10.1002/jcla.24472
Abstract: Mucosa‐associated lymphoid tissue lymphoma translocation protein 1 (MALT1) facilitates CD4+ T‐cell differentiation, immune response, inflammation, and osteoclastogenesis. This study aimed to explore the relation between MALT1 and treatment efficacy to tumor necrosis factor inhibitor (TNFi)… read more here.
Keywords: inflammation; spondylitis patients; inhibitor; treatment ... See more keywords
Exosomes derived from microRNA-21 overexpressed adipose tissue-derived mesenchymal stem cells alleviate spine osteoporosis in ankylosing spondylitis mice.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of tissue engineering and regenerative medicine"
DOI: 10.1002/term.3304
Abstract: MicroRNA-21 (miR-21) can induce proliferation and differentiation of mesenchymal stem cells (MSCs) to promote bone formation, we therefore aimed to investigate whether exosomes derived from miR-21 overexpressing adipose tissue-derived MSCs (AD-MSCs) could improve spine osteoporosis… read more here.
Keywords: mice; ankylosing spondylitis; spine osteoporosis; tissue ... See more keywords
Serum Sclerostin and Bone Morphogenetic Protein-2 Levels in Patients with Ankylosing Spondylitis: A Meta-Analysis
Sign Up to like & getrecommendations! Published in 2019 at "Calcified Tissue International"
DOI: 10.1007/s00223-019-00542-z
Abstract: Various studies have investigated the serum sclerostin and bone morphogenetic protein-2 (BMP-2) levels in patients with ankylosing spondylitis (AS), but the results were inconsistent. The aim of this meta-analysis was to synthetically assess the associations… read more here.
Keywords: levels patients; ankylosing spondylitis; sclerostin; analysis ... See more keywords
Aberrant antigen processing and presentation: Key pathogenic factors leading to immune activation in Ankylosing spondylitis.
Sign Up to like & getrecommendations! Published in 2021 at "Seminars in immunopathology"
DOI: 10.1007/s00281-020-00833-w
Abstract: The strong association of HLA-B*27 with ankylosing spondylitis (AS) was first reported nearly 50 years ago. However, the mechanistic link between HLA-B*27 and AS has remained an enigma. While 85-90% of AS patients possess HLA-B*27,… read more here.
Keywords: processing presentation; antigen processing; ankylosing spondylitis; hla ... See more keywords
Clinical utility of the ASDAS index in comparison with BASDAI in patients with ankylosing spondylitis (Axis Study)
Sign Up to like & getrecommendations! Published in 2017 at "Rheumatology International"
DOI: 10.1007/s00296-017-3814-2
Abstract: The objective of the study was to study the clinical utility of the Ankylosing Spondylitis Disease Activity Score (ASDAS) for the assessment of disease activity in ankylosing spondylitis (AS) patients, compared to the Bath Ankylosing… read more here.
Keywords: clinical utility; basdai; study; ankylosing spondylitis ... See more keywords
Serum CCL11 level is associated with radiographic spinal damage in patients with ankylosing spondylitis
Sign Up to like & getrecommendations! Published in 2018 at "Rheumatology International"
DOI: 10.1007/s00296-018-4073-6
Abstract: The clinical significance of C–C motif chemokine11 (CCL11) in bone metabolism in ankylosing spondylitis (AS) is not clearly elucidated. Thus, this cross-sectional study aimed to compare serum levels of CCL11 between patients with AS and… read more here.
Keywords: ankylosing spondylitis; levels ccl11; damage patients; serum ... See more keywords