A Quenched Annexin V‐Fluorophore for the Real‐Time Fluorescence Imaging of Apoptotic Processes In Vitro and In Vivo
Sign Up to like & getrecommendations! Published in 2020 at "Advanced Science"
DOI: 10.1002/advs.202002988
Abstract: Abstract Annexin‐based probes have long been used to study apoptotic cell death, which is of key importance to many areas of biological research, drug discovery, and clinical applications. Although apoptosis is a dynamic biological event… read more here.
Keywords: real time; apoptosis; fluorescence imaging; annexin ... See more keywords
Annexin A1, Annexin A2, and Dyrk 1B are upregulated during GAS1‐induced cell cycle arrest
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.26226
Abstract: GAS1 is a pleiotropic protein that has been investigated because of its ability to induce cell proliferation, cell arrest, and apoptosis, depending on the cellular or the physiological context in which it is expressed. At… read more here.
Keywords: cell; dyrk; annexin; cell arrest ... See more keywords
Reduced Annexin A3 in schizophrenia
Sign Up to like & getrecommendations! Published in 2019 at "European Archives of Psychiatry and Clinical Neuroscience"
DOI: 10.1007/s00406-019-01048-3
Abstract: The cellular and molecular mechanisms underlying onset and development of schizophrenia have not yet been completely elucidated, but the association of disturbed neuroplasticity and inflammation has gained particular relevance recently. These mechanisms are linked to… read more here.
Keywords: schizophrenia; reduced annexin; annexin; inflammation ... See more keywords
Cross-reactivity between annexin A2 and Beta-2-glycoprotein I in animal models of antiphospholipid syndrome
Sign Up to like & getrecommendations! Published in 2017 at "Immunologic Research"
DOI: 10.1007/s12026-016-8840-8
Abstract: Antiphospholipid syndrome (APS) affects coagulation and the brain by autoimmune mechanisms. The major antigen in APS is beta-2-glycoprotein I (β2-GPI) is known to complex with annexin A2 (ANXA2), and antibodies to ANXA2 have been described… read more here.
Keywords: antiphospholipid syndrome; anxa2 antibodies; annexin; beta glycoprotein ... See more keywords
Preeclampsia: a defect in decidualization is associated with deficiency of Annexin A2.
Sign Up to like & getrecommendations! Published in 2019 at "American journal of obstetrics and gynecology"
DOI: 10.1016/j.ajog.2019.11.1250
Abstract: BACKGROUND Decidualization defects in the endometrium have been demonstrated at the time of delivery in women with severe preeclampsia (sPE) and linger for years, suggesting a maternal contribution to the pathogenesis of this condition. Global… read more here.
Keywords: spe; annexin; anxa2; preeclampsia ... See more keywords
Transgelin-2 contributes to proliferation and progression of hepatocellular carcinoma via regulating Annexin A2.
Sign Up to like & getrecommendations! Published in 2020 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2020.01.028
Abstract: Hepatocellular carcinoma (HCC) is one of the most common malignant tumors, but its pathogenesis is not clear. This study found that the expression of TAGLN2 mRNA and protein in HCC was higher than that in… read more here.
Keywords: hepatocellular carcinoma; carcinoma; contributes proliferation; annexin ... See more keywords
EphB2 activates CREB-dependent expression of Annexin A1 to regulate dendritic spine morphogenesis.
Sign Up to like & getrecommendations! Published in 2021 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2021.11.011
Abstract: Dendritic spines are the postsynaptic structure to mediate signal transduction in neural circuitry, whose function and plasticity are regulated by organization of their molecular architecture and by the expression of target genes and proteins. EphB2,… read more here.
Keywords: dendritic spine; annexin; expression; spine morphogenesis ... See more keywords
Involvement of the annexin A1‐Fpr anti‐inflammatory system in the ocular allergy
Sign Up to like & getrecommendations! Published in 2019 at "European Journal of Pharmacology"
DOI: 10.1016/j.ejphar.2018.11.008
Abstract: Abstract Annexin A1 (ANXA1)‐formyl peptide receptor (Fpr) system is potent effective mediators in the control of the inflammatory response. In this study, we evaluate the potential involvement of the Fpr family in the protective effect… read more here.
Keywords: system; annexin; fpr; mice ... See more keywords
Molecular characterization of Schistosoma mansoni tegument annexins and comparative analysis of antibody responses following parasite infection.
Sign Up to like & getrecommendations! Published in 2019 at "Molecular and biochemical parasitology"
DOI: 10.1016/j.molbiopara.2019.111231
Abstract: Schistosomes are parasitic blood flukes that infect approximately 250 million people worldwide. The disease known as schistosomiasis, is the second most significant tropical parasitic disease after malaria. Praziquantel is the only effective drug currently licensed… read more here.
Keywords: molecular characterization; tegument; annexin; analysis ... See more keywords
Assessment of annexin A5 and annexin A2 levels as biomarkers for pre-eclampsia: A pilot study.
Sign Up to like & getrecommendations! Published in 2017 at "Pregnancy hypertension"
DOI: 10.1016/j.preghy.2017.03.006
Abstract: Deficient anticoagulant activity of annexin A5 and deficient profibrinolytic activity of annexin A2 have been linked to increased risk of thrombotic events. Placental dysfunction due to fibrin deposition/microthrombi has been implicated in the pathogenesis of… read more here.
Keywords: pilot study; annexin annexin; annexin; study ... See more keywords
YAP-dependent proliferation by a small molecule targeting annexin A2
Sign Up to like & getrecommendations! Published in 2021 at "Nature Chemical Biology"
DOI: 10.1038/s41589-021-00755-0
Abstract: The transcriptional coactivator Yes-associated protein 1 (YAP) orchestrates a proproliferative transcriptional program that controls the fate of somatic stem cells and the regenerative responses of certain tissues. As such, agents that activate YAP may hold therapeutic… read more here.
Keywords: dependent proliferation; yap dependent; small molecule; annexin ... See more keywords