Estimation of sample size in randomized controlled trials in multiple sclerosis studying annualized relapse rates: A systematic review.
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DOI: 10.1177/13524585211052400
Abstract: BACKGROUND In multiple sclerosis (MS) studies, the most appropriate model for the distribution of the number of relapses was shown to be the negative binomial (NB) distribution. OBJECTIVE To determine whether the sample-size estimation (SSE)… read more here.
Keywords: sample size; multiple sclerosis; relapse rates; annualized relapse ... See more keywords