Direct synthesis of annulated indoles through palladium-catalyzed double alkylations
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DOI: 10.1039/d0qo00135j
Abstract: A facile, one-step synthesis of annulated indoles from (N–H) indoles and dibromoalkanes was developed through a palladium-catalyzed double alkylation process. The reaction proceeds through a palladium-catalyzed norbornene-mediated C2-alkylation of indoles and subsequent regioselective cyclization. The… read more here.
Keywords: annulated indoles; catalyzed double; palladium catalyzed; synthesis annulated ... See more keywords