Cascade reaction to 1H-pyrazoles from hydrazones via sodium Ni-trite promoted dual C–C/C–N formation, annulation and aromatization with 1,2-dichloroethane
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DOI: 10.1016/j.cclet.2021.02.025
Abstract: Abstract A novel route for tandem C–C/C–N formation, annulation and aromatization of hydrazones with 1,2-dichloroethane to synthesize 1H-pyrazoles has been developed. Furthermore, the 1,2-dichloroethane serves as alkylation reagent in good to excellent yields. This methodology… read more here.
Keywords: annulation aromatization; reaction; formation annulation;
Acid-promoted furan annulation and aromatization: An access to benzo[b]furan derivatives
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DOI: 10.1016/j.tet.2017.11.049
Abstract: Abstract An unprecedented PTSA-promoted furan annulation and aromatization in one pot has been developed. This process offers a simple and efficient synthetic route for the construction of various highly substituted benzo[b]furan derivatives, which are widely… read more here.
Keywords: benzo furan; furan annulation; promoted furan; annulation aromatization ... See more keywords
Regioselective Synthesis of Pyrazolo[1,5-a]pyridine via TEMPO-Mediated [3 + 2] Annulation-Aromatization of N-Aminopyridines and α,β-Unsaturated Compounds.
Sign Up to like & getrecommendations! Published in 2022 at "Organic letters"
DOI: 10.1021/acs.orglett.2c00035
Abstract: A TEMPO-mediated [3 + 2] annulation-aromatization protocol for the preparation of pyrazolo[1,5-a]pyridines from N-aminopyridines and α,β-unsaturated compounds was developed. The procedure offered multisubstituted pyrazolo[1,5-a]pyridines in good to excellent yield with high and predictable regioselectivity. The… read more here.
Keywords: annulation aromatization; aminopyridines unsaturated; tempo mediated; unsaturated compounds ... See more keywords