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Published in 2022 at "Organic letters"
DOI: 10.1021/acs.orglett.2c02180
Abstract: An NHC-catalyzed enantio- and diastereoselective [3 + 2] annulation of α-bromoenals with bisoxindoles is developed, affording efficient access to various spirocyclic bisoxindole alkaloids. This protocol tolerates a broad substrates scope, with various spirocyclic bisoxindoles obtained…
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Keywords:
quaternary stereocenters;
catalyzed annulation;
annulation;
annulation bisoxindoles ... See more keywords