DABCO-mediated [4 + 4]-domino annulation reactions of ynones and α-cyano-α,β-unsaturated ketones: Mechanisms and the role of DABCO
Sign Up to like & getrecommendations! Published in 2021 at "Computational and Theoretical Chemistry"
DOI: 10.1016/j.comptc.2021.113396
Abstract: Abstract As natural products with important biological activities, eight-membered cyclic ethers can be achieved in good yields by the [4 + 4] domino annulation reactions of ynones and α-cyano-α,β-unsaturated ketones mediated by DABCO under mild conditions. To… read more here.
Keywords: annulation reactions; ynones cyano; dabco; domino annulation ... See more keywords
Synthesis of Germacyclic Compounds by Cyclization and Annulation Reactions Utilizing In Situ Generated Germyl Cations
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DOI: 10.1021/acs.organomet.1c00141
Abstract: Germyl cations are one of the heavier group 14 element analogues of carbocations and have been extensively studied for their structures, spectroscopic features, and reactivities to various molecule... read more here.
Keywords: germacyclic compounds; annulation reactions; germyl cations; cyclization annulation ... See more keywords
Insights into N-heterocyclic carbene-catalyzed [3 + 4] annulation reactions of 2-bromoenals with N-Ts hydrazones
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DOI: 10.1039/c8qo00716k
Abstract: The possible mechanisms and the origin of the stereoselectivity of the N-heterocyclic carbene (NHC)-catalyzed [3 + 4] annulation reaction of 2-bromoenal with N-Ts hydrazone have been investigated using density functional theory (DFT). The general mechanism… read more here.
Keywords: annulation; annulation reactions; nhc catalyzed; reaction ... See more keywords
Formal [5+1] annulation reactions of dielectrophilic peroxides: facile access to functionalized dihydropyrans.
Sign Up to like & getrecommendations! Published in 2020 at "Chemical communications"
DOI: 10.1039/d0cc05565d
Abstract: A general [5+1] annulation reaction, which utilized 4-bromo- or 4-mesyloxy-but-2-enyl peroxides as unique five-atom bielectrophilic synthons to participate in the C-C and the subsequent umpolung C-O bond-forming reactions with C1 nucleophiles, has been developed for… read more here.
Keywords: annulation; annulation reactions; dielectrophilic peroxides; formal annulation ... See more keywords
Insights into N-heterocyclic carbene and Lewis acid cooperatively catalyzed oxidative [3 + 3] annulation reactions of α,β-unsaturated aldehyde with 1,3-dicarbonyl compounds
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DOI: 10.1039/d0qo00091d
Abstract: Unravelling the origin of stereoselectivity and chemoselectivity is one of the most challenging questions in the field of N-heterocyclic carbene (NHC) catalysis. Recently, Lewis acid (LA) additives were found to be key additives for improving… read more here.
Keywords: lewis acid; annulation reactions; dicarbonyl compounds; stereoselectivity ... See more keywords
Regiodivergent (3 + 2) annulation reactions of oxyallyl cations
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DOI: 10.1039/d2sc06999g
Abstract: We report a new method for the regiodivergent dearomative (3 + 2) reaction between 3-substituted indoles and oxyallyl cations. Access to both regioisomeric products is possible and is contingent on the presence or absence of… read more here.
Keywords: annulation; oxyallyl cations; annulation reactions; reactions oxyallyl ... See more keywords
Recent Advances on Annulation Reactions with Allyl and Propargyl Sulfonium Salts
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DOI: 10.1055/a-1578-2911
Abstract: Allyl and propargyl sulfonium salts are readily available reagents that have recently emerged as versatile building blocks for the assembly of cyclic skeletons. As an alternative to classical sulfonium salts, allyl and propargyl sulfonium salts… read more here.
Keywords: annulation reactions; sulfonium salts; sulfonium; allyl propargyl ... See more keywords