[2 + 3] Annulative Coupling of Tetrahydroisoquinolines with Aryliodonio diazo compounds To Access 1,2,4-Triazolo[3,4-a]isoquinolines.
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DOI: 10.1021/acs.orglett.2c02442
Abstract: Base promoted one-pot annulative coupling of 1,2,3,4-tetrahydroisoquinolines (THIQs) with hypervalent iodine(III) species aryliodonio diazo compounds has been devised for the direct construction of 1,2,4-triazolo[3,4-a]isoquinoline derivatives at room temperature in open air for the first time.… read more here.
Keywords: triazolo; annulative coupling; diazo compounds; tetrahydroisoquinolines aryliodonio ... See more keywords
Annulative coupling of vinylboronic esters: aryne-triggered 1,2-metallate rearrangement
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DOI: 10.1039/d2sc02623f
Abstract: A stereoselective annulative coupling of a vinylboronic ester ate-complex with arynes producing cyclic borinic esters has been developed. An annulation reaction that proceeded through the formation of two C–C bonds and a C–B bond was… read more here.
Keywords: coupling vinylboronic; metallate rearrangement; annulative coupling; vinylboronic esters ... See more keywords