TMEM16A (ANO1) as a therapeutic target in cystic fibrosis.
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DOI: 10.1016/j.coph.2022.102206
Abstract: Cystic fibrosis (CF) is a multi-organ genetic disease caused by loss of function of CFTR, a cAMP-regulated chloride channel expressed in epithelial cells. In airway epithelia, CFTR-dependent chloride secretion is required to humidify mucosal surface… read more here.
Keywords: cystic fibrosis; tmem16a; tmem16a ano1; ano1 therapeutic ... See more keywords